NDLI: Compression of Microcapsules I: Effect of Excipients and Pressure on Drug Release

Content Provider	Scilit
Author	Prapaitrakul, Waruwan Whitworth, Clyde W.
Copyright Year	1989
Description	Journal: Drug Development and Industrial Pharmacy Microcapsules containing phenylpropanolamine-resin complexes were compressed with various diluents. Compression of microcapsules produced an increase in the release rate. An average reduction of 0.50 hours was observed when Emdex or Fast Flo Lactose were compared to Avicel at various pressures (35 to 281 MPa). Increasing the amount of microcapsules in the formulation reduced the T50% with all three diluents
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/03639048909052518
Ending Page	2053
Page Count	5
Starting Page	2049
ISSN	03639045
e-ISSN	15205762
DOI	10.3109/03639048909052518
Journal	Drug Development and Industrial Pharmacy
Issue Number	12
Volume Number	15
Language	English
Publisher	Informa UK Limited
Publisher Date	1989-01-01
Access Restriction	Open
Subject Keyword	Journal: Drug Development and Industrial Pharmacy Pharmacology and Pharmacy Drug Release Compression of Microcapsules Effect of Excipients
Content Type	Text
Subject	Organic Chemistry Drug Discovery Pharmacology Pharmaceutical Science

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Compression of Microcapsules I: Effect of Excipients and Pressure on Drug Release