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Comorbidities and Risk Factors for Severe Outcomes in COVID-19 Patients in Saudi Arabia: A Retrospective Cohort Study
| Content Provider | Scilit |
|---|---|
| Author | Shaikh, Fatema S. Aldhafferi, Nahier Buker, Areej Alqahtani, Abdullah Dey, Subhodeep Abdulhamid, Saema AlBuhairi, Dalal Ali Mahaii Alkabour, Raha Saud Abdulaziz Atiyah, Waad Sami O. Chrouf, Sara Bachar Alshehri, Abdussalam Olatunji, Sunday Olusanya Almuhaideb, Abdullah M. Alshahrani, Mohammed S. AlMunsour, Yousof Abdul-Salam, Vahitha B. |
| Copyright Year | 2021 |
| Description | Purpose: The first novel coronavirus disease-19 (COVID-19) case in the Kingdom of Saudi Arabia (KSA) was reported in Qatif in March 2020 with continual increase in infection and mortality rates since then. In this study, we aim to determine risk factors which effect severity and mortality rates in a cohort of hospitalized COVID-19 patients in KSA. Method: We reviewed medical records of hospitalized patients with confirmed COVID-19 positive results via reverse-transcriptase-polymerase-chain-reaction (RT-PCR) tests at Prince Mohammed Bin Abdulaziz Hospital, Riyadh between May and August 2020. Data were obtained for patient's demography, body mass index (BMI), and comorbidities. Additional data on patients that required intensive care unit (ICU) admission and clinical outcomes were recorded and analyzed with Python Pandas. Results: A total of 565 COVID-19 positive patients were inducted in the study out of which, 63 (11.1%) patients died while 101 (17.9%) patients required ICU admission. Disease incidences were significantly higher in males and non-Saudi nationals. Patients with cardiovascular, respiratory, and renal diseases displayed significantly higher association with ICU admissions (pppp=0.010] diseases were at significantly higher risk for mortality among the positive patients. There were no significant differences in mortality rates or ICU admissions among males and females, and across different age groups, BMIs and nationalities. Hospitalized patients with cardiovascular comorbidity had the highest risk of death (HR=2.9, CI 1.7– 5.0; p=0.020). Conclusion: Independent risk factors for critical outcomes among COVID-19 in KSA include cardiovascular, respiratory and renal comorbidities. |
| Related Links | https://www.dovepress.com/getfile.php?fileID=72559 |
| Ending Page | 2183 |
| Page Count | 15 |
| Starting Page | 2169 |
| ISSN | 11782390 |
| DOI | 10.2147/jmdh.s317884 |
| Journal | Journal of multidisciplinary healthcare |
| Volume Number | 14 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2021-08-01 |
| Access Restriction | Open |
| Subject Keyword | Oncology Covid-19 Sars-cov-2 Mortality Rate Comorbidities Risk Factors |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nursing Medicine |
