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Thyroid hormone replacement for nephrotic syndrome patients with euthyroid sick syndrome: a meta-analysis
| Content Provider | Scilit |
|---|---|
| Author | Liu, Huixin Yan, Wenjun Xu, Gaosi |
| Copyright Year | 2014 |
| Description | To assess the efficacy of thyroid hormone replacement therapy for nephrotic syndrome (NS) patients associated with euthyroid sick syndrome (ESS). The Cochrane library, ISI, Ovid, PubMed, Chinese Biomedicine Database were searched, and reference list of relevant articles were selected. Randomized controlled trials (RCTs) or quasi-RCTs with thyroid hormone replacement on NS patients associated with ESS were included in this analysis. Six trials (329 participants) were included. Meta-analysis showed that thyroid hormone replacement therapy can significantly increase the completely remission rate [OR = 3.04, 95% confidence interval (CI): 3.04-1.88, p < 0.00001] and total response rate (OR = 4.63, 95% CI: 2.46-8.71, p < 0.00001) of NS patients associated with ESS. No side effect was observed during the follow-up period. There was no obvious publication bias in the mete-analysis studies. Thyroid hormone replacement therapy significantly increases the remission of ESS in patients with NS. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/0886022X.2014.949559?needAccess=true |
| Ending Page | 1365 |
| Page Count | 6 |
| Starting Page | 1360 |
| ISSN | 0886022X |
| e-ISSN | 15256049 |
| DOI | 10.3109/0886022x.2014.949559 |
| Journal | Renal Failure |
| Issue Number | 9 |
| Volume Number | 36 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2014-08-12 |
| Access Restriction | Open |
| Subject Keyword | Medical Laboratory Technology Thyroid Hormone Replacement Euthyroid Sick Syndrome Meta-analysis Nephrotic Syndrome |
| Content Type | Text |
| Resource Type | Article |
| Subject | Critical Care and Intensive Care Medicine Nephrology |
