Loading...
Please wait, while we are loading the content...
Similar Documents
Antiidiotypes As Bacterial Vaccines
| Content Provider | Scilit |
|---|---|
| Author | Stein, K. E. |
| Copyright Year | 2018 |
| Description | This chapter demonstrates that anti-idiotype (anti-Id) vaccines have a place in the armamentarium of bacterial vaccines. The ability to purify and completely characterize an anti-Id, particularly a monoclonal antibody, gives this type of vaccine an advantage over some bacterial vaccines that consist of heterogeneous material or even whole cells. Anti-Id may be useful in stimulating anti- polysaccharide (PS) responses in individuals with immunodeficiencies that render them unresponsive to PS antigens. Anti-Id vaccines, in practice, may not be very different from antigen vaccines except that they enter the regulatory pathway of the immune system at a different place. During the course of an immune response, following a single immunization with a bacterial PS, oscillating waves of antibody and anti-Id have been observed. A high proportion of invasive bacterial infections is caused by encapsulated organisms such as Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae. Book Name: Biological Applications of Anti-Idiotypes |
| Related Links | https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1201/9781351070225-1&type=chapterpdf |
| DOI | 10.1201/9781351070225-1 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2018-01-18 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Biological Applications of Anti-idiotypes Antibody Antigen Bacterial Vaccines Single Immunization Heterogeneous Material Chapter Demonstrates |
| Content Type | Text |
| Resource Type | Chapter |
