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A Perspective of Ultrasound-Related Micro/Nano Cancer Therapy
| Content Provider | Scilit |
|---|---|
| Author | Zheng, Tingting Chen, Yun Peng, Jiao Shi, Yu Zhang, Jun Xiao, Haitao Chen, Xiangmei Huang, Yongcan Pei, Tao Zhang, Zhuxia Zhang, Xue Bai, Xiaohe Liu, Li Wang, Jinrui |
| Copyright Year | 2020 |
| Description | Ultrasound (US) is currently identified not only as a noninvasive diagnosis tool but also as a promising mineral- and/or non-invasive therapeutic tool in hospitals. According to ultrasound adjustability, which includes adjusting frequency, intensity, mode, and waveform, theranostic treatment can be performed in 144different parameter combinations, of which high-intensity focused ultrasound and low-intensity focused ultrasound are two frequently performed treatments, especially for cancer treatment. Most important traits of cancer theranostic focused ultrasound among others are sonothermal effect, ultrasonic cavitation effect, sonoporation effect, sonodynamic effect, and ultrasound targeted drug delivery. To date, high-intensity focused ultrasound (HIFU) ablation has already been applied clinically; however, low-intensity focused ultrasound (LIFU) targeted cancer therapy is still in preclinical study phase. One of the main challenges for its clinical transition ascribes to its low therapeutic efficiency. Scientists therefore induce hybrid micro-/nanoparticles, which play a role as contrast and/or drug delivery carriers in a microscopic scale. In assistance of hybrid micro-/nanobubbles and correlative smart nanoparticles, ultrasound (e.g., LIFU)-related cancer therapy has been verified as a promising choice with minimal side effects or non-trauma. In this chapter, we will discuss the use of HIFU and LIFU approaches to cancer therapy in combination with micro-/nanoparticles to maximize therapeutic effects. Book Name: Nanoparticle Drug Delivery Systems for Cancer Treatment |
| Related Links | https://content.taylorfrancis.com/books/download?dac=C2019-0-05229-X&isbn=9780429341250&doi=10.1201/9780429341250-6&format=pdf |
| Ending Page | 184 |
| Page Count | 42 |
| Starting Page | 143 |
| DOI | 10.1201/9780429341250-6 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2020-02-19 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Nanoparticle Drug Delivery Systems for Cancer Treatment Biomedical Engineering Treatment Cancer Therapy Focused Ultrasound Theranostic Promising Intensity Focused |
| Content Type | Text |
| Resource Type | Chapter |