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Clinical and Histologic Features Differentiating Non-Relapsing Colitis from First Attacks of Inflammatory Bowel Disease
| Content Provider | Scilit |
|---|---|
| Author | Schumacher, G. Sandstedt, B. Möllby, R. Kollberg, B. |
| Copyright Year | 1991 |
| Description | This is a study of first attacks of colitis, evaluating prospectively the overall course with repeated histologic, clinical, laboratory, and initial microbiologic examinations. Forty-two attacks of colitis could after a follow-up period of 5.5 years be separated into relapsing and non-relapsing types. Relapse was chosen as a prerequisite for a final diagnosis of inflammatory bowel disease. In the non-relapsing group 72% of the patients harboured enteropathogenic bacteria. An insidious onset of diarrhoeal symptoms was highly discriminant of inflammatory bowel disease, whereas an acute onset mostly occurred in patients with non-relapsing colitis. Macroscopic differentiation at sigmoidoscopy was not possible. Distorted crypt architecture (92%) and/or basal plasmacytosis (77%) at initial biopsies strongly indicated inflammatory bowel disease but was also found transiently in patients with infectious colitis (19%). Thus, careful microbiologic and clinical investigation and repeated histologic examinations are necessary to distinguish infectious colitis from inflammatory bowel disease. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/00365529109025025 |
| Ending Page | 161 |
| Page Count | 11 |
| Starting Page | 151 |
| ISSN | 00365521 |
| e-ISSN | 15027708 |
| DOI | 10.3109/00365529109025025 |
| Journal | Scandinavian Journal of Gastroenterology |
| Issue Number | 2 |
| Volume Number | 26 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1991-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Scandinavian Journal of Gastroenterology Pathology Acute Self-limited Colitis Crohn's Disease Infectious Colitis Inflammatory Bowel Disease Non-relapsing Colitis Transient Colitis Ulcerative Colitis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Gastroenterology |
