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Microscopic colitis in patients with ulcerative colitis or Crohn’s disease: a retrospective observational study and review of the literature
| Content Provider | Scilit |
|---|---|
| Author | Wickbom, Anna Bohr, Johan Nyhlin, Nils Eriksson, Anders Lapidus, Annika Münch, Andreas Ung, Kjell-Arne Vigren, Lina Öst, Åke Tysk, Curt |
| Copyright Year | 2018 |
| Description | Journal: Scandinavian Journal of Gastroenterology Onset of microscopic colitis (MC) in patients with ulcerative colitis (UC) or Crohn's disease (CD), or vice versa, has been reported occasionally but the subject is not well described. We therefore report a retrospective observational study of such patients and review the literature. Forty-six Swedish gastroenterology clinics were contacted about patients with diagnoses of both inflammatory bowel disease (IBD) and MC. Publications were searched on PubMed. We identified 31 patients with onset of MC after a median (range) of 20 (2-52) years after diagnosis of IBD, or vice versa; 21 UC patients developed collagenous colitis (CC) (n = 16) or lymphocytic colitis (LC) (n = 5); nine CD patients developed CC (n = 5) or LC (n = 4); one CC patient developed CD. Of the 21 UC patients, 18 had extensive disease, whereas no consistent phenotype occurred in CD. Literature review revealed 27 comprehensive case reports of patients with diagnoses of both IBD and MC. Thirteen MC patients developed IBD, of which four required colectomy. Fourteen IBD patients later developed MC. There were incomplete clinical data in 115 additional reported patients. Altogether 173 patients with occurrence of both IBD and MC were found. The most common finding in our patients was onset of CC in a patient with UC. Although these are likely random associations of two different disorders, MC should be considered in the patient with UC or CD if there is onset of chronic watery diarrhoea without endoscopic relapse of IBD. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.1080/00365521.2018.1430252?needAccess=true |
| Ending Page | 416 |
| Page Count | 7 |
| Starting Page | 410 |
| ISSN | 00365521 |
| e-ISSN | 15027708 |
| DOI | 10.1080/00365521.2018.1430252 |
| Journal | Scandinavian Journal of Gastroenterology |
| Issue Number | 4 |
| Volume Number | 53 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2018-03-16 |
| Access Restriction | Open |
| Subject Keyword | Journal: Scandinavian Journal of Gastroenterology Gastroenterology and Hepatology Collagenous Colitis Crohn's Disease Inflammatory Bowel Disease Lymphocytic Colitis Microscopic Colitis Ulcerative Colitis |
| Content Type | Text |
| Subject | Gastroenterology |
