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The Development of Adoptive T-Cell Immunotherapies for Cancer
| Content Provider | Scilit |
|---|---|
| Author | Dow, David J. Howe, Steven J. Talekar, Mala K. Johnson, Laura A. |
| Copyright Year | 2019 |
| Description | The field of cancer immunotherapy began in the 19th century with William Coley's studies injecting live Streptococcus bacilli bacteria and heat-killed bacterial extracts into primary tumors resulting in an induced durable remission of inoperable sarcoma (Burdick, 1937 ; Decker and Safdar, 2009). Fast forward to today where the successful development of CTLA-4 and PD-1 checkpoint inhibitors, along with the recent FDA approval of Kymriah and Yescarta, two CAR-T cell immunotherapies, heralds a new era in cancer medicine. Book Name: Drug Discovery and Development |
| Related Links | https://content.taylorfrancis.com/books/download?dac=C2017-0-46032-1&isbn=9781315113470&doi=10.1201/9781315113470-9&format=pdf |
| Ending Page | 144 |
| Page Count | 26 |
| Starting Page | 119 |
| DOI | 10.1201/9781315113470-9 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2019-11-21 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Drug Discovery and Development Oncology Fda Heralds Forward William Century Began Cell Immunotherapies Kymriah |
| Content Type | Text |
| Resource Type | Chapter |