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Children with Persistent Cough – Outcome with Treatment and Role of Moraxella catarrhalis?
| Content Provider | Scilit |
|---|---|
| Author | Gottfarb, Peter Brauner, Annelie |
| Copyright Year | 1994 |
| Description | 52 children with severe cough persisting for more than 10 days were randomized to treatment with amoxycillin/clavulanic acid or placebo in a prospective double-blinded study. Clinically suspected cases of pertussis were excluded, yet 12 (23%) of the children had laboratory verified pertussis infection. The nasopharyngeal colonization showed a predominance of Moraxella catarrhalis which was isolated in 37 (71%) children. Streptococcus pneumoniae and Haemophilus influenzae were isolated in 11 (20%) and 16 (30%) children, respectively. The antibiotic-treated group had a significantly better recovery in both the pediatrician's estimation (p = 0.02) and the independent parental judgement (p = 0.002). These findings are consistent with the view that Moraxella catarrhalis could be directly involved in the pathogenesis of persistent cough in children. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/00365549409011812 |
| Ending Page | 551 |
| Page Count | 7 |
| Starting Page | 545 |
| ISSN | 00365548 |
| e-ISSN | 16511980 |
| DOI | 10.3109/00365549409011812 |
| Journal | Scandinavian journal of infectious diseases |
| Issue Number | 5 |
| Volume Number | 26 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1994-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Scandinavian Journal of Infectious Diseases Infectious Diseases Children Moraxella Catarrhalis Persistent Cough Pertussis Treatment Haemophilus Amoxycillin/clavulanic |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Immunology and Microbiology Microbiology (medical) |
