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Prevalence of Inflammatory Bowel Disease among Relatives of Patients with Ulcerative Colitis
| Content Provider | Scilit |
|---|---|
| Author | Monsen, U. Brostrom, O. Nordenvall, B. Sörstad, J. Hellers, G. |
| Copyright Year | 1987 |
| Description | The familial occurrence of inflammatory bowel disease (IBD) was investigated among 963 patients with ulcerative colitis (UC) diagnosed in 1955–1979 in Stockholm County. For 76 patients who had a relative with IBD a pedigree was drawn. The diagnoses of the diseased relatives were verified. There was a general prevalence of 7.9% for IBD among relatives. In 80% one relative was affected, in most cases a first-degree relative with UC. Sihship was the commonest relationship. No concordance for UC was found among three pairs of monozygotic twins. The prevalence of UC in first-degree relatives was 15 times higher than in non-relatives. The age of onset was significantly lower among patients with a family history for UC; they also had a higher incidence of total colitis. The prevalence of Crohn's disease in first-degree relatives of patients with UC was almost 3.5 times higher than in non-relatives. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/00365528708991882 |
| Ending Page | 218 |
| Page Count | 5 |
| Starting Page | 214 |
| ISSN | 00365521 |
| e-ISSN | 15027708 |
| DOI | 10.3109/00365528708991882 |
| Journal | Scandinavian Journal of Gastroenterology |
| Issue Number | 2 |
| Volume Number | 22 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1987-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Scandinavian Journal of Gastroenterology Legal Medicine Inflammatory Bowel Disease Prevalence Ulcerative Colitis Patients with Ulcerative Disease Among Relatives |
| Content Type | Text |
| Resource Type | Article |
| Subject | Gastroenterology |
