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Super-resolution binding activated localization microscopy through reversible change of DNA conformation
| Content Provider | Scilit |
|---|---|
| Author | Szczurek, Aleksander Birk, Udo Knecht, Hans Dobrucki, Jerzy Mai, Sabine Cremer, Christoph |
| Copyright Year | 2018 |
| Description | Methods of super-resolving light microscopy (SRM) have found an exponentially growing range of applications in cell biology, including nuclear structure analyses. Recent developments have proven that Single Molecule Localization Microscopy (SMLM), a type of SRM, is particularly useful for enhanced spatial analysis of the cell nucleus due to its highest resolving capability combined with very specific fluorescent labeling. In this commentary we offer a brief review of the latest methodological development in the field of SMLM of chromatin designated DNA Structure Fluctuation Assisted Binding Activated Localization Microscopy (abbreviated as fBALM) as well as its potential future applications in biology and medicine. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.1080/19491034.2017.1419846?needAccess=true https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973136/pdf |
| Ending Page | 189 |
| Page Count | 8 |
| Starting Page | 182 |
| ISSN | 19491034 |
| e-ISSN | 19491042 |
| DOI | 10.1080/19491034.2017.1419846 |
| Journal | Nucleus |
| Issue Number | 1 |
| Volume Number | 9 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2018-12-31 |
| Access Restriction | Open |
| Subject Keyword | Journal: Nucleus Microscopic Research Chromatin Dna Fbalm, Smlm Nucleus Single Molecule Localization Super-resolution Microscopy |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Medicine |