NDLI: Plasma soluble urokinase plasminogen activator receptor (suPAR) levels in systemic lupus erythematosus

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Plasma soluble urokinase plasminogen activator receptor (suPAR) levels in systemic lupus erythematosus

Content Provider	Scilit
Author	Toldi, Gergely Szalay, Balazs Bekő, Gabriella Bocskai, Márta Deák, Magdolna Kovács, László Vásárhelyi, Barna Balog, Attila
Copyright Year	2012
Description	Objective: Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker of systemic inflammation. We aimed to characterize plasma suPAR levels in SLE patients. Methods: We measured plasma suPAR, C reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in 89 SLE patients and 29 healthy controls. Results: suPAR and ESR values were higher in SLE than in controls, while CRP levels were comparable. ROC analysis of suPAR levels indicated a cut-off value of 5.70 ng/mL to distinguish patients with high disease activity (SLEDAI >8). Conclusion: suPAR might be an objective marker for identifying SLE patients with active disease.
Related Links	https://core.ac.uk/download/pdf/80768715.pdf http://www.tandfonline.com/doi/pdf/10.3109/1354750X.2012.728623
Ending Page	763
Page Count	6
Starting Page	758
ISSN	1354750X
e-ISSN	13665804
DOI	10.3109/1354750x.2012.728623
Journal	Biomarkers
Issue Number	8
Volume Number	17
Language	English
Publisher	Informa UK Limited
Publisher Date	2012-08-20
Access Restriction	Open
Subject Keyword	Journal: Biomarkers Rheumatology Systemic Plasminogen Activator Active Disease Urokinase Plasminogen Soluble Urokinase Plasma Supar Supar Levels Activator Receptor
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Medicine Clinical Biochemistry Biochemistry

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