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Soluble urokinase plasminogen activator receptor informs on the progression course after multiple injuries
| Content Provider | Scilit |
|---|---|
| Author | Patrani, Maria Tsaganos, Thomas Kotzampassi, Katerina Paraschos, Michael Katsenos, Chrysostomos Giamarellos-Bourboulis, Evangelos J. Mandragos, Konstantinos |
| Copyright Year | 2016 |
| Description | Purpose: The purpose of this study is to study the use of soluble urokinase plasminogen activator receptor (suPAR) for the prognosis of multiple organ dysfunction (MOF) after multiple traumas. Methods: Serum suPAR was measured within the first 24 h after multiple injuries in 85 patients. Measurements were repeated after 4 d or at sepsis onset. Results: Odds ratio for trauma-associated MOF was 4.09 (p: 0.026) with admission suPAR greater than 8 ng/ml. More than 40% increases of suPAR were associated with odds ratio 9.33 (p: 0.047) for severe sepsis. Conclusions: suPAR is a useful surrogate biomarker for development of MOF and severe sepsis after multiple traumas. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/1354750X.2016.1171911 |
| Ending Page | 664 |
| Page Count | 5 |
| Starting Page | 660 |
| ISSN | 1354750X |
| e-ISSN | 13665804 |
| DOI | 10.3109/1354750x.2016.1171911 |
| Journal | Biomarkers |
| Issue Number | 7 |
| Volume Number | 21 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2016-04-27 |
| Access Restriction | Open |
| Subject Keyword | Journal: Biomarkers Medical Laboratory Technology Multiple Organ Failure Severe Sepsis Supar Trauma |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Medicine Clinical Biochemistry Biochemistry |
