NDLI: The Use of GM-CSF and G-CSF in the Treatment of Acute Leukemias

Please wait, while we are loading the content...

The Use of GM-CSF and G-CSF in the Treatment of Acute Leukemias

Content Provider	Scilit
Author	Harousseau, Jean-Luc Wu, Depei
Copyright Year	1995
Description	The administration of HGF after chemotherapy for patients with acute leukemia does not appear to decrease the CR rate or to increase the relapse rate while the risk of leukemic clone stimulation in this context is probably low, even in AML. Time to neutrophil recovery is generally reduced but in only a few studies does this result in a better CR rate. Up to now, the event free survival and the overall survival has never been prolonged by the administration of HGF after induction chemotherapy only. The attractive approach of priming by HGF has not yet proved useful and many questions still remain regarding the optimal administration. Accordingly, one cannot recommend routine use of HGF in the treatment of acute leukemia. Longer follow up of the ongoing trials and further studies are still required in order to appreciate the exact impact of the use of GM-CSF or G-CSF for this particular indication.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/10428199509059638
Ending Page	412
Page Count	8
Starting Page	405
ISSN	10428194
e-ISSN	10292403
DOI	10.3109/10428199509059638
Journal	Leukemia & Lymphoma
Issue Number	5-6
Volume Number	18
Language	English
Publisher	Informa UK Limited
Publisher Date	1995-01-01
Access Restriction	Open
Subject Keyword	Journal: Leukemia & Lymphoma Hematology Gm-csf G-csf Acute Leukemia Treatment
Content Type	Text
Resource Type	Article
Subject	Hematology Cancer Research Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in