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Cell membrane camouflaged nanoparticles: a new biomimetic platform for cancer photothermal therapy
| Content Provider | Scilit |
|---|---|
| Author | Wu, Minliang Le, Wenjun Mei, Tianxiao Wang, Yuchong Chen, Bingdi Liu, Zhongmin Xue, Chunyu |
| Copyright Year | 2019 |
| Description | Abstract: Targeted drug delivery by nanoparticles (NPs) is an essential technique to achieve the ideal therapeutic effect for cancer. However, it requires large amounts of work to imitate the biomarkers on the surface of the cell membrane and cannot fully retain the bio-function and interactions among cells. Cell membranes have been studied to form biomimetic NPs to achieve functions like immune escape, targeted drug delivery, and immune modulation, which inherit the ability to interact with the in vivo environments. Currently, erythrocyte, leukocyte, mesenchymal stem cell, cancer cell and platelet have been applied in coating photothermal agents and anti-cancer drugs to achieve increased photothermal conversion efficiency and decreased side effects in cancer ablation. In this review, we discuss the recent development of cell membrane-coated NPs in the application of photothermal therapy and cancer targeting. The underlying biomarkers of cell membrane-coated nanoparticles (CMNPs) are discussed, and future research directions are suggested. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588714/pdf https://www.dovepress.com/getfile.php?fileID=50540 |
| Ending Page | 4448 |
| Page Count | 18 |
| Starting Page | 4431 |
| e-ISSN | 11782013 |
| DOI | 10.2147/ijn.s200284 |
| Journal | International Journal of Nanomedicine |
| Volume Number | 14 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2019-06-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: International Journal of Nanomedicine Biomaterials Pharmacology and Pharmacy Cancer Targeting Cell Membrane Nanoparticles Photothermal Therapy |
| Content Type | Text |
| Resource Type | Article |