NDLI: Synthesis of Quinazolines and Imidazo[1,2-c]quinazolines with the Aid of a Low-Valent Titanium Reagent

Content Provider	Scilit
Author	Shi, Daqing Wang, Juxian Shi, Chunling Rong, Liangce Zhuang, Qiya Hu, Hongwen
Copyright Year	2004
Description	A short and facile synthesis of a series of quinazolines and imidazo[1,2-c]quinazolines was accomplished in good yields via the novel reductive cyclization of 2-nitrobenzyl amines or 2-(2-nitrophenyl)imidazoles with ortho-ester, aldehydes or ketones promoted by $TiCl_{4}$/Zn system. The structures were established by spectroscopic data and confirmed by X-ray analysis.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2004-822893.pdf
Ending Page	1100
Page Count	3
Starting Page	1098
ISSN	09365214
e-ISSN	14372096
DOI	10.1055/s-2004-822893
Journal	Synlett
Issue Number	6
Volume Number	2004
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2004-03-25
Access Restriction	Open
Subject Keyword	Organic Chemistry Low-valent Titanium 2-nitrobenzyl Amine 2-(2-nitrophenyl)imidazole
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry

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Synthesis of Quinazolines and Imidazo[1,2-c]quinazolines with the Aid of a Low-Valent Titanium Reagent