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Update on Diagnosis and Management of Essential Thrombocythemia
| Content Provider | Scilit |
|---|---|
| Author | Gisslinger, Heinz |
| Copyright Year | 2006 |
| Description | Patients with essential thrombocythemia carry a high risk for thromboembolic and bleeding events but they have an almost normal life expectancy. A careful evaluation of the medical history and an exact diagnosis is mandatory to estimate each patient's risk for morbidity and to choose the most appropriate treatment measure. In patients with the need of cytoreductive therapy, the benefits of therapy have to outweigh the potential risks of drug toxicities. Hydroxyurea is the most useful cytoreductive drug for elderly patients; in younger persons, interferon α or anagrelide may be the drugs of choice. The combination of anagrelide with acetylsalicylic acid may be contraindicated in patients with a history of bleeding. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-942764.pdf |
| Ending Page | 436 |
| Page Count | 7 |
| Starting Page | 430 |
| ISSN | 00946176 |
| e-ISSN | 10989064 |
| DOI | 10.1055/s-2006-942764 |
| Journal | Seminars in Thrombosis and Hemostasis |
| Issue Number | 4 |
| Volume Number | 32 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2006-06-29 |
| Access Restriction | Open |
| Subject Keyword | Journal: Seminars in Thrombosis and Hemostasis Critical Care Medicine Keywordsessential Thrombocythemia Cytoreductive Therapy Jak2v617f Mutation Interferon Α |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hematology Cardiology and Cardiovascular Medicine |
