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Effect of Streptozotocin Diabetes on Sialic Acid Content and Glycoprotein Binding of Isolated Hepatocytes
| Content Provider | Scilit |
|---|---|
| Author | Durand, G. Appel, M. Durand, D. Davy, J. Féger, J. Agneray, J. |
| Editor | Dumont, J. P. |
| Copyright Year | 1980 |
| Description | The possible correlation between sialic acid content of hepatocyte plasma membranes, and their binding capacity was investigated. For that purpose, $|^{3}$H| asialotransferrin binding was tested with hepatocytes from both normal and streptozotocin treated rats. The observed decrease in binding capacity was parallel to a decrease in the sialic acid content. Insulin therapy restored simultaneously normal blood glucose level, hepatic membrane sialic acid content and binding capacity. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-996259.pdf |
| Ending Page | 251 |
| Page Count | 5 |
| Starting Page | 247 |
| ISSN | 00185043 |
| e-ISSN | 14394286 |
| DOI | 10.1055/s-2007-996259 |
| Journal | Hormone and Metabolic Research |
| Issue Number | 06 |
| Volume Number | 12 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 1980-06-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Hormone and Metabolic Research Key-words Sialic Acid Hepatocyte Asialoglycoprotein Streptozotocin Diabetes |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry (medical) Endocrinology, Diabetes and Metabolism Biochemistry Clinical Biochemistry Endocrinology |
