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Leaving Group Ability in Nucleophilic Aromatic Amination by Sodium Hydride–Lithium Iodide Composite
| Content Provider | Scilit |
|---|---|
| Author | Pang, Jia Hao Ong, Derek Yiren Watanabe, Kohei Takita, Ryo Chiba, Shunsuke |
| Copyright Year | 2019 |
| Description | The methoxy group is generally considered as a poor leaving group for nucleophilic substitution reactions. This work verified the superior ability of the methoxy group in nucleophilic amination of arenes mediated by the sodium hydride and lithium iodide through experimental and computational approaches. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0039-1690010.pdf |
| Ending Page | 398 |
| Page Count | 6 |
| Starting Page | 393 |
| ISSN | 00397881 |
| e-ISSN | 1437210X |
| DOI | 10.1055/s-0039-1690010 |
| Journal | Synthesis |
| Issue Number | 03 |
| Volume Number | 52 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2019-07-24 |
| Access Restriction | Open |
| Subject Keyword | Journal: Synthesis Organic Chemistry Nucleophilic Amination Concerted Aromatic Substitution Methoxy Group Dft Calculations |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Catalysis |