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Genetic polymorphisms of cytochrome P450 enzymes: CYP2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5 in the Croatian population
| Content Provider | Scilit |
|---|---|
| Author | Ganoci, Lana Božina, Tamara Skvrce, Nikica Mirošević Lovrić, Mila Mas, Petar Božina, Nada |
| Copyright Year | 2017 |
| Abstract | Background: Data on the frequency of pharmacogenetic polymorphisms in the Croatian population are limited. We determined and analyzed frequencies for the most importantMethods: 2637 subjects were included. Genotyping was performed by real-time polymerase chain reaction (PCR) using TaqMan® DME or TaqMan® SNP Genotyping Assays, and by PCR, and PCR-RFLP analysis.Results: ForConclusions: The frequency of the CYP allelic variants, genotypes, and predicted phenotypes in the Croatian population is in accordance with the other European populations, between the values of published data for Middle European and Mediterranean populations. |
| Related Links | http://www.degruyter.com/downloadpdf/j/dmdi.2017.32.issue-1/dmpt-2016-0024/dmpt-2016-0024.xml |
| Ending Page | 21 |
| Page Count | 11 |
| Starting Page | 11 |
| ISSN | 23638907 |
| e-ISSN | 23638915 |
| DOI | 10.1515/dmpt-2016-0024 |
| Journal | Drug metabolism and personalized therapy |
| Issue Number | 1 |
| Volume Number | 32 |
| Language | English |
| Publisher | Walter de Gruyter GmbH |
| Publisher Date | 2017-01-01 |
| Access Restriction | Open |
| Subject Keyword | Drug Metabolism and Personalized Therapy Medical Laboratory Technology Croatian Population Cyp2c9 Cyp2c19 Cyp2d6 Cyp3a4 Cyp3a5 Cytochrome P450 (cyp) Pharmacogenetics Polymorphisms Journal: Drug metabolism and personalized therapy, Vol- 32 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pharmacology, Toxicology and Pharmaceutics Pharmacology (medical) |