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Development of a Luminescence Immunoassay for Follitropin Suitable for Clinical Routine
| Content Provider | Scilit |
|---|---|
| Author | Biro, G. Samira, Asfoura Butz, H. Leicht, E. Weinges, K. F. |
| Copyright Year | 1991 |
| Abstract | We developed a luminescence immunoassay (LIA) for follitropin, based on the synthesis of a follitropin-N-(4-aminobutyl)-N-ethylisoluminol conjugate. The luminescence tracer was purified by gel chromatography. Antibody-bound and non-bound tracer fractions were separated by using a second antibody reagent bound to magnetic particles. The assay can be performed within 24 hours and is sufficiently sensitive for the measurement of all clinically relevant follitropin concentrations including the subnormal range. |
| Related Links | https://edoc.hu-berlin.de/bitstream/18452/12437/1/cclm.1991.29.3.189.pdf http://www.degruyter.com/downloadpdf/j/cclm.1991.29.issue-3/cclm.1991.29.3.189/cclm.1991.29.3.189.xml |
| Ending Page | 192 |
| Page Count | 4 |
| Starting Page | 189 |
| ISSN | 14346621 |
| e-ISSN | 14374331 |
| DOI | 10.1515/cclm.1991.29.3.189 |
| Journal | Clinical Chemistry and Laboratory Medicine (CCLM) |
| Issue Number | 3 |
| Volume Number | 29 |
| Language | English |
| Publisher | Walter de Gruyter GmbH |
| Publisher Date | 1991-01-01 |
| Access Restriction | Open |
| Subject Keyword | Clinical Chemistry and Laboratory Medicine (cclm) Analytical Chemistry Antibody Chromatography Tracer Routine Sufficiently Follitropin Ethylisoluminol Luminescence Immunoassay Journal: Clinical Chemistry and Laboratory Medicine (CCLM), Vol- 29 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry (medical) Clinical Biochemistry |