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Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome
| Content Provider | Scilit |
|---|---|
| Author | Balderman, Sophia R. Li, Allison J. Hoffman, Corey M. Frisch, Benjamin J. Goodman, Alexandra N. LaMere, Mark W. Georger, Mary A. Evans, Andrew G. Liesveld, Jane L. Becker, Michael W. Calvi, Laura M. |
| Copyright Year | 2016 |
| Description | Key Points An in vivo model of MDS displays time-dependent defects in HSPCs and in microenvironmental populations. Normalization of the marrow microenvironment alters disease progression and transformation and improves hematopoietic function. |
| Related Links | https://ashpublications.org/blood/article-pdf/127/5/616/1394720/616.pdf |
| Ending Page | 625 |
| Page Count | 10 |
| Starting Page | 616 |
| DOI | 10.1182/blood-2015-06-653113 |
| Journal | Blood |
| Issue Number | 5 |
| Volume Number | 127 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2016-02-04 |
| Access Restriction | Open |
| Subject Keyword | Research and Experimental Medicine Bone Marrow Model Hematopoietic Marrow Microenvironment Function Hspcs Defects Murine Journal: Blood (Vol- 84, Issue- 5) |
| Content Type | Text |
| Resource Type | Article |