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Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways
| Content Provider | Scilit |
|---|---|
| Author | Popescu, Narcis I. Silasi, Robert Keshari, Ravi S. Girton, Alanson Burgett, Tarea Zeerleder, Sacha S. Gailani, David Gruber, Andras Lupu, Florea Coggeshall, K. Mark |
| Copyright Year | 2018 |
| Description | Key PointsPGN infusion mimics the systemic inflammation and coagulopathy observed in late-stage B anthracis challenge. PGN directly activates the extrinsic coagulation and promotes contact pathway amplification in nonhuman primates. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107880/pdf |
| Ending Page | 860 |
| Page Count | 12 |
| Starting Page | 849 |
| DOI | 10.1182/blood-2017-10-813618 |
| Journal | Blood |
| Issue Number | 8 |
| Volume Number | 132 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2018-08-23 |
| Access Restriction | Open |
| Subject Keyword | Research and Experimental Medicine Baboons Systemic Coagulation Peptidoglycan Nonhuman Intravascular Late Anthracis Directly Pgn Journal: Blood (Vol- 106, Issue- 8) |
| Content Type | Text |
| Resource Type | Article |