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Congenital nonspherocytic hemolytic anemia with an unstable hexokinase variant
Content Provider | Scilit |
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Author | Board, Pg Trueworthy, R. Smith, Je Moore, K. |
Copyright Year | 1978 |
Description | We report a family with a new hexokinase variant that gives rise to nonspherocytic hemolytic anemia in one apparently homozygous family member. The variant enzyme has a normal pH optimum, normal reaction kinetics, and normal electrophoretic properties, but has reduced activity and is apparently inactivated rapidly as the affected erythrocytes age. |
Related Links | https://ashpublications.org/blood/article-pdf/51/1/111/205406/111.pdf |
Ending Page | 118 |
Page Count | 8 |
Starting Page | 111 |
DOI | 10.1182/blood.v51.1.111.bloodjournal511111 |
Journal | Blood |
Issue Number | 1 |
Volume Number | 51 |
Language | English |
Publisher | American Society of Hematology |
Publisher Date | 1978-01-01 |
Access Restriction | Open |
Subject Keyword | Medical Laboratory Technology Erythrocytes Hexokinase Unstable Electrophoretic Hemolytic Anemia Rapidly Nonspherocytic Hemolytic Journal: Blood (Vol- 3, Issue- 1) |
Content Type | Text |
Resource Type | Article |