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A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice
| Content Provider | Scilit |
|---|---|
| Author | Jain, Reema Sheridan, Julie Policheni, Antonia Heinlein, Melanie Gandolfo, Luke C. Dewson, Grant Smyth, Gordon K. Sansom, Stephen N. Fu, Naiyang Visvader, Jane E. Holländer, Georg A. Strasser, Andreas Gray, Daniel H. D. |
| Copyright Year | 2017 |
| Description | Key Points MCL-1 is essential, but BCL-2 and BCL-XL are dispensable, for TEC survival and thymic function. Epidermal growth factor upregulates MCL-1 in TECs. |
| Related Links | https://ashpublications.org/blood/article-pdf/130/23/2504/1404119/blood771576.pdf |
| Ending Page | 2515 |
| Page Count | 12 |
| Starting Page | 2504 |
| DOI | 10.1182/blood-2017-03-771576 |
| Journal | Blood |
| Issue Number | 23 |
| Volume Number | 130 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2017-12-07 |
| Access Restriction | Open |
| Subject Keyword | Research and Experimental Medicine Survival Function Mcl Bcl Axis Epidermal Dispensable Critical Epithelial Journal: Blood (Vol- 137, Issue- 23) |
| Content Type | Text |
| Resource Type | Article |