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Nonviral RNA chimeric antigen receptor–modified T cells in patients with Hodgkin lymphoma
| Content Provider | Scilit |
|---|---|
| Author | Svoboda, Jakub Rheingold, Susan R. Gill, Saar I. Grupp, Stephan A. Lacey, Simon F. Kulikovskaya, Irina Suhoski, Megan M. Melenhorst, J. Joseph Loudon, Brandon Mato, Anthony R. Nasta, Sunita Dwivedy Landsburg, Daniel J. Youngman, Matthew R. Levine, Bruce L. Porter, David L. June, Carl H. Schuster, Stephen J. |
| Copyright Year | 2018 |
| Description | Key Points Manufacturing CART19 by transfecting autologous T cells with messenger RNA is feasible. Targeting CD19+ B cells in cHL using nonviral RNA CART19 was well tolerated and resulted in transient responses in a pilot study. |
| Related Links | http://www.bloodjournal.org/content/early/2018/06/20/blood-2018-03-837609.full.pdf |
| Ending Page | 1026 |
| Page Count | 5 |
| Starting Page | 1022 |
| DOI | 10.1182/blood-2018-03-837609 |
| Journal | Blood |
| Issue Number | 10 |
| Volume Number | 132 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2018-09-06 |
| Access Restriction | Open |
| Subject Keyword | Hematology Research and Experimental Medicine Autologous Antigen Cd19 Messenger Transient Chimeric Hodgkin Tolerated Nonviral Rna Journal: Blood (Vol- 115, Issue- 10) |
| Content Type | Text |
| Resource Type | Article |