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CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age
| Content Provider | Scilit |
|---|---|
| Author | Gekas, Christos Graf, Thomas |
| Copyright Year | 2013 |
| Description | Key Points: Integrin CD41, thought to absent on adult HSCs, marks a novel subset of myeloid-biased long-term HSCs that becomes prevalent with age. Loss of CD41 leads to transplantable hematopoietic defects that affect HSC survival and maintenance and are, in part, mediated by platelet loss. |
| Related Links | http://www.bloodjournal.org/content/bloodjournal/121/22/4463.full.pdf |
| Ending Page | 4472 |
| Page Count | 10 |
| Starting Page | 4463 |
| DOI | 10.1182/blood-2012-09-457929 |
| Journal | Blood |
| Issue Number | 22 |
| Volume Number | 121 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2013-05-30 |
| Access Restriction | Open |
| Subject Keyword | Research and Experimental Medicine Hematopoietic Adult Survival Cd41 Myeloid Biased Defects Absent Maintenance Transplantable Journal: Blood (Vol- 135, Issue- 22) |
| Content Type | Text |
| Resource Type | Article |