NDLI: Plasma beta-thromboglobulin: differentiation between intravascular and extravascular platelet destruction

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Plasma beta-thromboglobulin: differentiation between intravascular and extravascular platelet destruction

Content Provider	Scilit
Author	Han, P. Turpie, Ag Genton, E.
Copyright Year	1979
Description	To elucidate the usefulness of beta-thromboglobulin (beta TG) in the differentiation of the mechanism of thrombocytopenia, plasma beta TG concentration was measured in one patient with amegakaryocytic thrombocytopenia, four patients with autoimmune thrombocytopenia (ATP), two patients with thrombotic thrombocytopenia (TTP), and one patient with thrombocytopenia secondary to disseminated intravascular coagulation (DIC). Plasma beta TG was not measurable in amegakaryocytic thrombocytopenia, was normal in ATP, and was increased in TTP and DIC. These data indicate that in thrombocytopenic patients, increased plasma beta TG concentration may result from intravascular platelet consumption with release of platelet constituents in contrast to extravascular platelet destruction by the macrophage-monocyte system.
Related Links	https://ashpublications.org/blood/article-pdf/54/5/1192/582576/1192.pdf
Ending Page	1196
Page Count	5
Starting Page	1192
DOI	10.1182/blood.v54.5.1192.1192
Journal	Blood
Issue Number	5
Volume Number	54
Language	English
Publisher	American Society of Hematology
Publisher Date	1979-11-01
Access Restriction	Open
Subject Keyword	Hematology Differentiation Platelet Dic Intravascular Thromboglobulin Plasma Beta Beta Tg Journal: Blood (Vol- 80, Issue- 5)
Content Type	Text
Resource Type	Article

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