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Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels
| Content Provider | Scilit |
|---|---|
| Author | O’Sullivan, Jamie M. O’Connell, Niamh M. O’Donnell, James S. Lavin, Michelle Aguila, Sonia Schneppenheim, Sonja Dalton, Niall Jones, Kenneth L. Ryan, Kevin White, Barry Byrne, Mary Rafferty, Marie Doyle, Mairead M. Nolan, Margaret Preston, Roger J. S. Budde, Ulrich James, Paula Paola, Jorge Di |
| Copyright Year | 2017 |
| Description | Key Points Patients registered with low VWF have significant bleeding phenotypes that cannot be explained by concomitant bleeding disorders. Low VWF levels in the range of 30 to 50 IU/dL are predominantly due to reduced VWF synthesis/secretion rather than enhanced clearance. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881608/pdf |
| Ending Page | 2353 |
| Page Count | 10 |
| Starting Page | 2344 |
| DOI | 10.1182/blood-2017-05-786699 |
| Journal | Blood |
| Issue Number | 21 |
| Volume Number | 130 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 2017-11-23 |
| Access Restriction | Open |
| Subject Keyword | Hematology Pathophysiology Antigen Ddavp Plasma Vwf Significant Bleeding Low Vwf Levels Journal: Blood (Vol- 134, Issue- 21) |
| Content Type | Text |
| Resource Type | Article |