Loading...
Please wait, while we are loading the content...
Similar Documents
Matching of histocompatibility (HL-A) antigens for platelet transfusion
| Content Provider | Scilit |
|---|---|
| Author | Mittal, Kk Ruder, Ea Green, D. |
| Copyright Year | 1976 |
| Description | The average in vivo platelet survival was measured by both per cent recoveries (%R) and half-lives (t 1/2) of 51Cr-labeled platelets in 69 transfusions given to 43 thrombacytopenic patients. The results demonstrated that (1) increase in the number of HL-A incompatibilities in the platelet donor was significantly associated with decreased %R and t 1/2 of the infused platelets; (2) survival of transfused platelets from HL-A-matched single donors was consistently superior to those pooled from several grossly mismatched donors; and (3) survival of platelets infused when patients had circulating lymphocytotoxic antibodies was consistently lower than when patients did not have such antibodies, regardless of whether it was the first, second, or third such infusion. |
| Related Links | https://ashpublications.org/blood/article-pdf/47/1/31/203794/31.pdf |
| Ending Page | 41 |
| Page Count | 11 |
| Starting Page | 31 |
| DOI | 10.1182/blood.v47.1.31.bloodjournal47131 |
| Journal | Blood |
| Issue Number | 1 |
| Volume Number | 47 |
| Language | English |
| Publisher | American Society of Hematology |
| Publisher Date | 1976-01-01 |
| Access Restriction | Open |
| Subject Keyword | Hematology Survival Antibodies Antigens Platelets Incompatibilities Transfusions 51cr Lymphocytotoxic Thrombacytopenic Journal: Blood (Vol- 2, Issue- 1) |
| Content Type | Text |
| Resource Type | Article |