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Shrimp sensitization in house dust mite allergic patients
| Content Provider | SAGE Publishing |
|---|---|
| Author | Ukleja-Sokołowska, Natalia Gawrońska-Ukleja, Ewa Lis, Kinga Żbikowska-Gotz, Magdalena Adamczak, Rafał Sokołowski, Łukasz Bartuzi, Zbigniew |
| Copyright Year | 2020 |
| Abstract | Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to Dermatophagoides pteronyssinus and 57.8% to Dermatophagoides farinae. In total, 128 (55.2%) patients were sensitized to both HDM species and 143 (61.6%) to at least one. Slightly over a quarter (25.4%) of patients were sensitized to shrimp. Of the 35 shrimp-sensitized patients, the sensitization to Der p 10 and Pen a 1 was found in 11 cases (31.4%). There was a strong correlation between IgE Pen a 1 and IgE Der p 10 concentrations. The results indicate that there are other allergens responsible for a high incidence of shrimp sensitization in HDM-sensitized patients. A high convergence of Der p 10 and Pen a 1 levels may indicate that the determination of just one of the above is reasonable. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/2058738420907188?download=true |
| ISSN | 03946320 |
| Volume Number | 34 |
| Journal | International Journal of Immunopathology and Pharmacology (IJI) |
| e-ISSN | 20587384 |
| DOI | 10.1177/2058738420907188 |
| Language | English |
| Publisher | Sage Publications UK |
| Publisher Date | 2020-03-05 |
| Publisher Place | London |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2020 |
| Subject Keyword | sensitization allergy house dust mite shrimp cross-reactivity tropomyosin |
| Content Type | Text |
| Resource Type | Article |
| Subject | Immunology and Allergy Pharmacology Immunology |
