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A highly selective fluorescent probe for the sensing of Cu2+ based on the hydrolysis of a quinoline-2-carboxylate and its application in cell imaging
| Content Provider | SAGE Publishing |
|---|---|
| Author | You, Qihua Zhuo, Yihua Feng, Yadong Xiao, Yujuan Zhang, Yanyu Zhang, Lei |
| Copyright Year | 2020 |
| Abstract | A highly selective OFF–ON fluorescent probe is developed for the sensing of Cu2+ based on the hydrolysis of a quinoline-2-carboxylate moiety. The probe is weakly fluorescent due to esterification of the phenolic group. Upon treatment with 1 equiv. of Cu2+, the probe exhibits strong fluorescence at 570 nm. The probe also exhibits high selectivity for Cu2+ over other cations with a low detection limit of 0.2 μM, which is sensitive enough to meet the standard of the World Health Organization for Cu2+ in drinking water (30 μM). Moreover, the probe shows a very low cell cytotoxicity, and imaging experiments demonstrate that the probe can be used for the sensing of Cu2+ in living cells. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/1747519820973929?download=true |
| Starting Page | 315 |
| Ending Page | 321 |
| Page Count | 7 |
| ISSN | 17475198 |
| Issue Number | 3-4 |
| Volume Number | 45 |
| Journal | Journal of Chemical Research (CHL) |
| e-ISSN | 20476507 |
| DOI | 10.1177/1747519820973929 |
| Language | English |
| Publisher | Sage Publications UK |
| Publisher Date | 2020-11-30 |
| Publisher Place | London |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2020 |
| Subject Keyword | cell imaging Cu2+ sensing fluorescent probe quinoline-2-carboxylate |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry |
