NDLI: Colloidosomes constructed by the seamless connection of nanoparticles: a mobile and recyclable strategy to intelligent capsules

Content Provider	Royal Society of Chemistry (RSC)
Author	Xu, Yiting He§, Ning Jiang, Nina Xu, Binbin Dai, Lizong Chen, Guangjian Yuan, Conghui
Copyright Year	2011
Abstract	Colloidosomes constructed by the self-assembly of nanoparticles (NPs) on liquid–liquid interfaces have been demonstrated to be useful in many fields. However, the interspaces between NPs on the surface of colloidosomes barricade their application in small molecule encapsulation. Herein, fabrication of a new type of colloidosome built by the seamless connection of NPs via simply heating and quenching a type of core–shell structured NPs (CSNPs) aqueous system using oil as a template, is presented. These colloidosomes have a hollow structure and exhibit efficient small molecule encapsulation. More importantly, the colloidosomes can dissociate into single NPs and release the small target molecules encapsulated in interior of the colloidosomes at a temperature higher than the melting point of the CSNP shell. It is also shown that the dissociation temperature of colloidosomes can be controlled by simply adjusting the length of the PEG chains in the CSNP shell, which implies that these intelligent capsules have attractive application prospects in controlled drug release.
Starting Page	3366
Ending Page	3372
Page Count	7
File Format	HTM / HTML PDF
ISSN	1744683X
Volume Number	7
Issue Number	7
Journal	Soft Matter
DOI	10.1039/c0sm01128b
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Self-assembly Dissociative Drug prohibition law
Content Type	Text
Resource Type	Article
Subject	Chemistry Condensed Matter Physics

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