NDLI: UV exposure and protection against allergic airways disease

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UV exposure and protection against allergic airways disease

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Back cover

Photochemical & Photobiological Sciences Vol - 9 Issue - 3

Photochemical & Photobiological Sciences Vol - 9 Issue - 2

Photochemical & Photobiological Sciences Vol -8

Photochemical & Photobiological Sciences Vol -7

Photochemical & Photobiological Sciences Vol -6

Photochemical & Photobiological Sciences Vol -5

Photochemical & Photobiological Sciences Vol -4

Photochemical & Photobiological Sciences Vol -3

Photochemical & Photobiological Sciences Vol -2

UV exposure and protection against allergic airways disease

Content Provider	Royal Society of Chemistry (RSC)
Author	Lambert, Misty J. M. Thomas, Jennifer A Strickland, Deborah H. McGlade, Jacqueline P. Hart, Prue H. Gorman, Shelley
Copyright Year	2010
Abstract	Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity. Allergen-specific IgE levels control the immediate response whilst the interplay between airway mucosal antigen presenting cells, Th2 effector cells and CD4+CD25+ regulatory T cells control the late phase, cell-mediated response. Using two experimental systems in mice with ovalbumin and papain, respectively, as the allergens, UV irradiation of skin prior to allergen sensitisation reduced the expression of allergic airways disease, particularly the late phase response. In this review, the reduced Th2-driven, asthma-like responses in respiratory tissues of UV-irradiated mice are detailed. Possible mechanisms of UV regulation are debated. The potential beneficial effects of UV irradiation of skin in controlling allergic airways disease are discussed. This review gives some scientific understanding to century-old anecdotal reports that beach and mountain resort holidays associated with increased UV exposure are beneficial in asthma treatment.
Starting Page	571
Ending Page	577
Page Count	7
File Format	HTM / HTML PDF
ISSN	1474905X
Volume Number	9
Issue Number	4
Journal	Photochemical & Photobiological Sciences
DOI	10.1039/b9pp00136k
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Antigen Ovalbumin Mountain IL2RA Immunoglobulin E Interplay Entertainment Papain Mucous membrane T helper cell Asthma Immune system Allergen
Content Type	Text
Resource Type	Article
Subject	Physical and Theoretical Chemistry

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Anti-Interleukin-9 Antibody Increases the Effect of Allergen-Specific Immunotherapy in Murine Allergic Rhinitis

Bzqef detinitlve report t cells expressing specific elements regulate irnmunoglobu!in e production and airways responsiveness in vivo.

Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled Antigen

Traditional Medicinal Plants Conferring Protection Against Ovalbumin-Induced Asthma in Experimental Animals: A Review

Suppressive Effects of Bifidobacterium breve Strain M-16V on T-Helper Type 2 Immune Responses in a Murine Model

T follicular helper and TH2 cells in allergic responses

Interleukin‐16 aggravates ovalbumin‐induced allergic inflammation by enhancing Th2 and Th17 cytokine production in a mouse model

Basophils as a primary inducer of the T helper type 2 immunity in ovalbumin-induced allergic airway inflammation

A major house dust mite allergen disrupts the immunoglobulin e network by selectively cleaving cd23: innate protection by antiproteases (1995).

UV exposure and protection against allergic airways disease

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Bzqef detinitlve report t cells expressing specific elements regulate irnmunoglobu!in e production and airways responsiveness in vivo.

Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled Antigen

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UV exposure and protection against allergic airways disease