NDLI: Bioactive and electroactive response of flexible polythiophene:polyester nanomembranes for tissue engineering

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Back cover

Polymer Chemistry Vol - 3 Issue - 3

Polymer Chemistry Vol - 3 Issue - 2

Polymer Chemistry Vol -2

Polymer Chemistry Vol -1

Bioactive and electroactive response of flexible polythiophene:polyester nanomembranes for tissue engineering

Content Provider	Royal Society of Chemistry (RSC)
Author	Estrany, Francesc Valle, Luis J. del Armelin, Elaine Pérez-Madrigal, Maria M. Alemán, Carlos
Copyright Year	2012
Abstract	Properties of free-standing nanomembranes prepared by blending poly(3-thiophene methyl acetate) and poly(tetramethylene succinate), a soluble polythiophene derivative and a biodegradable polyester, respectively, have been examined. The outstanding flexibility and robustness of the nanomembranes floating in ethanol have been demonstrated through aspiration in pipette/release/shape recovery cycles, which were repeated without cracking the film. The blend retains the electrochemical properties (i.e. oxidation and reduction processes) of the individual conducting polymer in both physiological and organic environments. Hydrolytic and enzymatic degradation assays show that the degradation of the polyester domains produces the detachment of the conducting polymer domains. The cellular viability, which has been studied using four different cellular lines, is significantly higher for the blend than for the polyester, indicating that the former material is a potential bioactive platform for tissue engineering. Finally, the electrobioactivity of the individual materials and the blend coated with cellular monolayers shows some dependence on the cellular line.
Starting Page	979
Ending Page	991
Page Count	13
File Format	HTM / HTML PDF
ISSN	17599954
Volume Number	3
Issue Number	4
Journal	Polymer Chemistry
DOI	10.1039/c2py00584k
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Biodegradation Hydrolytic Polyester Polythiophene Ethanol Tissue engineering Substance dependence Thiophene Pipette Succinic acid Electrochemistry Conductive polymer Methyl acetate
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry Bioengineering Biomedical Engineering Polymers and Plastics

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