NDLI: Repeatable deep-tissue activation of persistent luminescent nanoparticles by soft X-ray for high sensitivity long-term in vivo bioimaging

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In situ thermomechanical testing methods for micro/nano-scale materials

Ultrafast injection-locked amplification in a thin-film distributed feedback microcavity

Monodisperse phase transfer and surface bioengineering of metal nanoparticles via a silk fibroin protein corona

Anti-counterfeiting patterns encrypted with multi-mode luminescent nanotaggants

NaYbF₄ nanoparticles as near infrared light excited inorganic photosensitizers for deep penetration in photodynamic therapy

Atomic-layer-deposited ultrafine MoS₂ nanocrystals on cobalt foam for efficient and stable electrochemical oxygen evolution

Repeatable deep-tissue activation of persistent luminescent nanoparticles by soft X-ray for high sensitivity long-term in vivo bioimaging

Simultaneous topographical, electrical and optical microscopy of optoelectronic devices at the nanoscale

Shape-controlled syntheses of metal oxide nanoparticles by the introduction of rare-earth metals

Directional elastic wave propagation in high-aspect-ratio photoresist gratings: liquid infiltration and aging

Integrating DNA strand displacement circuitry to the nonlinear hybridization chain reaction

Synergistic chemotherapeutic effect of sorafenib-loaded pullulan-Dox conjugate nanoparticles against murine breast carcinoma

Imaging and structural studies of DNA–protein complexes and membrane ion channels

Detecting the shape of anisotropic gold nanoparticles in dispersion with single particle extinction and scattering

High vacuum synthesis and ambient stability of bottom-up graphene nanoribbons

Controlled aggregation and cell uptake of thermoresponsive polyoxazoline-grafted superparamagnetic iron oxide nanoparticles

Diffusion doping in quantum dots: bond strength and diffusivity

Connecting quantum dots with enzymes: mediator-based approaches for the light-directed read-out of glucose and fructose oxidation

Mn-Doped ZnSe quantum dots initiated mild and rapid cation exchange for tailoring the composition and optical properties of colloid nanocrystals: novel template, new applications

Highly doped silicon nanowires by monolayer doping

Fully alloyed metal nanorods with highly tunable properties

Efficient perovskite solar cells by combination use of Au nanoparticles and insulating metal oxide

An anti-fouling nanoplasmonic SERS substrate for trapping and releasing a cationic fluorescent tag from human blood solution

Realization of efficient light out-coupling in organic light-emitting diodes with surface carbon-coated magnetic alloy nanoparticles

Defining the copper binding aptamotif and aptamer integrated recovery platform (AIRP)

A ten-electron (10e) thiolate-protected Au₂₉(SR)₁₉ cluster: structure prediction and a ‘gold-atom insertion, thiolate-group elimination’ mechanism

True non-contact atomic force microscopy imaging of heterogeneous biological samples in liquids: topography and material contrast

In situ mechanical investigation of carbon nanotube–graphene junction in three-dimensional carbon nanostructures

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Repeatable deep-tissue activation of persistent luminescent nanoparticles by soft X-ray for high sensitivity long-term in vivo bioimaging

Content Provider	Royal Society of Chemistry (RSC)
Author	Song, Xiao-Rong Lin, Xia-Hui Song, Liang Chen, Xiao-Feng Li, Juan Chen, Shan Yang, Huang-Hao
Copyright Year	2017
Abstract	Persistent luminescent nanoparticles (PLNPs) have emerged as important nanomaterials for biological imaging as a result of complete avoidance of tissue auto-fluorescence. However, the imaging sensitivity and long-term in vivo imaging are still limited due to the persistent luminescence that is rapidly decayed in vivo after an ex vivo excitation. To address this limitation, in vivo activation of PLNPs is highly desired. Herein, we present a new strategy for the activation of PLNPs (SrAl2O4:Eu2+) by using soft X-ray excitation. Importantly, as the soft X-ray light source possesses the advantage of deep tissue penetration, the PLNPs can be reactivated in vivo through living tissue using soft X-ray excitation. Furthermore, X-ray/persistent luminescence dual-modal imaging can be achieved to empower this strategy with high sensitivity. Our results suggest that this new strategy of in vivo energy charging in PLNPs would bring new insights for deep tissue and long-term bioimaging in living animals, and provide new perspectives for persistent luminescence bioimaging and therapeutic applications.
Starting Page	2718
Ending Page	2722
Page Count	5
File Format	HTM / HTML PDF
ISSN	20403364
Volume Number	9
Issue Number	8
Journal	Nanoscale
DOI	10.1039/c6nr09553d
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Luminescence Nanomaterials X-ray
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology

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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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Radiopaque tantalum oxide coated persistent luminescent nanoparticles as multimodal probes for in vivo near-infrared luminescence and computed tomography bioimaging.

Photostimulable near-infrared persistent luminescent nanoprobes for ultrasensitive and longitudinal deep-tissue bio-imaging.

NIR-persistent luminescent nanoparticles for bioimaging, principle and perspectives

The develop of persistent luminescence nanoparticles with excellent performances in cancer targeted bioimaging and killing: a review

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One-step synthesis of amino-functionalized ultrasmall near infrared-emitting persistent luminescent nanoparticles for in vitro and in vivo bioimaging.

Long-term in vivo biodistribution and toxicity study of functionalized near-infrared persistent luminescence nanoparticles.

Repeatable deep-tissue activation of persistent luminescent nanoparticles by soft X-ray for high sensitivity long-term in vivo bioimaging

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