NDLI: Electrokinetic flow control in microfluidic chips using a field-effect transistor

Content Provider	Royal Society of Chemistry (RSC)
Author	Dutta, Prashanta Horiuchi, Keisuke
Copyright Year	2006
Abstract	A field-effect transistor is developed to control flow in microfluidic chips by modifying the surface charge condition. In this investigation, zeta potential at a particular location is altered locally by applying a gate voltage, while zeta potential at other locations is maintained at its original value. This non-uniform zeta potential results in a secondary electroosmotic flow in the lateral direction, which is used for flow control in microgeometries. Here, microchannel structures and field-effect transistors are formed on polydimethylsiloxane (PDMS) using soft lithography techniques, and a micro particle image velocimetry technique is used to obtain high resolution velocity distribution in the controlled region. The flow control is observed at relatively low gate voltage (less than 50 V), and this local flow control is primarily due to current leakage through the interface between PDMS and glass layers. A leakage capacitance model is introduced to estimate the modified zeta potential for the straight channel case, and excellent agreement is obtained between the predicted and experimental zeta potential results. This leakage-current based field-effect is then applied to a T-channel junction to control flow in the branch channel. Experiments show that the amount of discharge in the branch channel can be controlled by modulating gate voltage.
Starting Page	714
Ending Page	723
Page Count	10
File Format	HTM / HTML PDF
ISSN	14730197
Volume Number	6
Issue Number	6
Journal	Lab on a Chip
DOI	10.1039/b600067c
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Subscribed
Subject Keyword	Control flow Soft lithography Electro-osmosis Zeta potential Field-effect transistor Particle image velocimetry Capacitance Polydimethylsiloxane PDMS
Content Type	Text
Resource Type	Article
Subject	Chemistry Nanoscience and Nanotechnology Biochemistry Bioengineering Biomedical Engineering

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