NDLI: Photodefinable polydimethylsiloxane (PDMS) for rapid lab-on-a-chip prototyping

Content Provider	Royal Society of Chemistry (RSC)
Author	Bhagat, Ali Asgar S. Jothimuthu, Preetha Papautsky, Ian
Copyright Year	2007
Abstract	In this paper, we introduce a new and simple method of patterning polydimethylsiloxane (PDMS) directly using benzophenone as a photoinitiator. The photodefinable PDMS mixture (photoPDMS) is positive-acting and only sensitive to light below 365 nm, permitting processing under normal ambient light. Features of the order of 100 µm, which are sufficiently small for most microfluidic applications, were successfully fabricated using this novel process. A parametric study of process parameters was performed to optimize the fabrication. As a demonstration, microfluidic channels of varying dimensions were successfully fabricated using this process and experimentally characterized using fluorescence microscopy. To further demonstrate photoPDMS potential, thin (<30 µm) free-standing films with through patterns were fabricated and successfully used as shadow masks. The photoPDMS process completely eliminates the need for a master, permits processing under normal ambient light conditions, and makes fabrication fast and simple. This process for rapid prototyping of low-cost, disposable LOCs can be accomplished without cleanroom facilities and thus can be employed for a wide range of applications.
Starting Page	1192
Ending Page	1197
Page Count	6
File Format	HTM / HTML PDF
ISSN	14730197
Volume Number	7
Issue Number	9
Journal	Lab on a Chip
DOI	10.1039/b704946c
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Subscribed
Subject Keyword	Cleanroom Micrometre Rapid prototyping Fluorescence microscope Polydimethylsiloxane Benzophenone Photoinitiator
Content Type	Text
Resource Type	Article
Subject	Chemistry Nanoscience and Nanotechnology Biochemistry Bioengineering Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Rapid prototyping of microfluidic systems using a PDMS/polymer tape composite

Compact fluorescence detection using in-fiber microchannels—its potential for lab-on-a-chip applications

Multilayer PDMS microfluidic chamber for controlling brain slice microenvironment

A vacuum manifold for rapid world-to-chip connectivity of complex PDMS microdevices

A disposable planar peristaltic pump for lab-on-a-chip

A portable pressure pump for microfluidic lab-on-a-chip systems using a porous polydimethylsiloxane (PDMS) sponge

Rapid prototyping of microfluidic devices with a wax printer

A toner-mediated lithographic technology for rapid prototyping of glass microchannels

Teflon films for chemically-inert microfluidic valves and pumps

Photodefinable polydimethylsiloxane (PDMS) for rapid lab-on-a-chip prototyping

Similar Documents

Rapid prototyping of microfluidic systems using a PDMS/polymer tape composite

Compact fluorescence detection using in-fiber microchannels—its potential for lab-on-a-chip applications

Multilayer PDMS microfluidic chamber for controlling brain slice microenvironment

A vacuum manifold for rapid world-to-chip connectivity of complex PDMS microdevices

A disposable planar peristaltic pump for lab-on-a-chip

A portable pressure pump for microfluidic lab-on-a-chip systems using a porous polydimethylsiloxane (PDMS) sponge

Rapid prototyping of microfluidic devices with a wax printer

A toner-mediated lithographic technology for rapid prototyping of glass microchannels

Teflon films for chemically-inert microfluidic valves and pumps

Photodefinable polydimethylsiloxane (PDMS) for rapid lab-on-a-chip prototyping