Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | Royal Society of Chemistry (RSC) |
|---|---|
| Author | Zhao, Changsheng Nie, Chuanxiong Xia, Yi Deng, Jie Cheng, Chong Wang, Rui |
| Copyright Year | 2015 |
| Abstract | A highly efficient, universal and convenient protocol is reported to fabricate antifouling, hemocompatible, and bactericidal membranes by physically blending antifouling nanogels and in situ silver nanoparticle immobilization. Firstly, nanogels are synthesized by one-step cross-linking co-polymerization of an antifouling monomer, poly(ethylene glycol) methacrylate (PEGMA), and an anchoring monomer, methylacrylic acid (MAA). Then, the nanogels are physically blended with a membrane matrix to generate nanogel embedded composite membranes. Finally, the in situ growth of silver nanoparticles in the composite membranes is successfully achieved by electrostatic adsorption of Ag+ ions and vitamin C reduction. The successful preparation of Ag-nanogel blended polymeric membranes has been confirmed by FTIR spectra and XPS patterns. The surface SEM images suggest that there are abundant Ag-nanogels embedded on the composite membrane surfaces. The cross-sectional SEM images give clear evidence that the Ag-nanogel immobilized composite membranes have well-maintained finger-like structure with increased porosity; meanwhile, the uniform distribution of the Ag-nanogels in the membrane matrix is confirmed by elemental EDX mapping. The systematic tests of water contact angle, static protein adsorption and ultrafiltration experiments indicate that the hydrophilicity, water flux, and antifouling properties of the composite membranes are substantially improved. More importantly, prolonged blood clotting time and suppressed platelet adhesion/activation indicate that the composite membranes have better blood compatibility and ultralow thrombotic potential. Bactericidal studies reveal that the modified membranes exhibit remarkable inhibition and killing capability toward both S. aureus and E. coli bacteria. The results reveal that robust antifouling, hemocompatible, and bactericidal composite membranes have been prepared via the proposed blending of nanogels and loading of Ag nanoparticles. This approach is believed to have great potential for fabricating various multifunctional membranes for industrial and clinical usage. |
| Starting Page | 9295 |
| Ending Page | 9304 |
| Page Count | 10 |
| File Format | HTM / HTML PDF |
| ISSN | 2050750X |
| Volume Number | 3 |
| Issue Number | 48 |
| Journal | Journal of Materials Chemistry B |
| DOI | 10.1039/c5tb01523e |
| Language | English |
| Publisher | Royal Society of Chemistry |
| Access Restriction | Open |
| Subject Keyword | Bactericide Silver nanoparticle Monomer Ethylene glycol Acid Extracellular matrix Nanogel Adsorption Vitamin C Porosity Discrete uniform distribution Water contact Protein Ultrafiltration Hydrophile Platelet Aureus Escherichia coli Bacteria |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Medicine Materials Science Biomedical Engineering |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|