NDLI: Rapid mineralization of porous gelatin scaffolds by electrodeposition for bone tissue engineering

Content Provider	Royal Society of Chemistry (RSC)
Author	Mo, Xiumei Feng, Wei He, Chuanglong Cao, Lijun Qiu, Kexin Wang, Hongsheng Wang, Jinwu Zhang, Fan Zhang, Yanzhong
Copyright Year	2012
Abstract	In bone tissue engineering, rapid mineralization of polymeric scaffolds is of particular importance in protecting the encapsulated therapeutic drugs or growth factors from loss and degradation. Here, we present a simple and rapid approach to the fabrication of mineralized porous scaffolds for bone tissue engineering. In this approach, three-dimensional (3-D) porous gelatin scaffolds were firstly fabricated by freeze-drying followed by an electrodeposition process for mineralization. We show that a high-quality apatite coating on the gelatin scaffold could be achieved within a couple of hours by electrodeposition. Increasing the deposition voltage or electrolyte temperature favored to the formation of large amounts of apatite coatings with compositions dominated by the hydroxyapatite crystals, whereas the presence of ultrasonic field facilitated the production of homogeneous apatite coatings. Moreover, biological assays indicated that the mineralized scaffolds exhibited better support for the proliferation and osteoblastic differentiation of MC3T3-E1 cells over a neat gelatin scaffold, especially for the case of mineralized scaffolds by electrodeposition at 60 °C. Therefore, the method developed would be highly desired for the rapid mineralization of polymer scaffolds in which biological molecules were loaded for functional bone tissue engineering applications.
Starting Page	2111
Ending Page	2119
Page Count	9
File Format	HTM / HTML PDF
ISSN	09599428
Volume Number	22
Issue Number	5
Journal	Journal of Materials Chemistry
DOI	10.1039/c1jm14631a
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Bone Tissue engineering Three-dimensional space Gelatin Freeze-drying Electroplating Apatite Electrolyte Hydroxylapatite Ultrasound MC3T3 Polymer
Content Type	Text
Resource Type	Article
Subject	Chemistry Materials Chemistry

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Rapid mineralization of porous gelatin scaffolds by electrodeposition for bone tissue engineering

Enhanced antibacterial activity and osteoinductivity of Ag-loaded strontium hydroxyapatite/chitosan porous scaffolds for bone tissue engineering

Freeze-dried multiscale porous nanofibrous three dimensional scaffolds for bone regenerations.

Rapid mineralization of hierarchical poly(l-lactic acid)/poly(ε-caprolactone) nanofibrous scaffolds by electrodeposition for bone regeneration

Rapid mineralization of hierarchical poly(l-lactic acid)/poly(ε-caprolactone) nanofibrous scaffolds by electrodeposition for bone regeneration

Large three-dimensional poly(glycerol sebacate)-based scaffolds – a freeze-drying preparation approach

Hierarchically designed injectable hydrogel from oxidized dextran, amino gelatin and 4-arm poly(ethylene glycol)-acrylate for tissue engineering application

Synthesis of Porous Carbonate Apatite/Gelatin Scaffolds Via Freeze Drying Method

Bone Tissue Regeneration by Collagen Scaffolds with Different Calcium Phosphate Coatings: Amorphous Calcium Phosphate and Low-Crystalline Apatite

Rapid mineralization of porous gelatin scaffolds by electrodeposition for bone tissue engineering

Similar Documents

Rapid mineralization of porous gelatin scaffolds by electrodeposition for bone tissue engineering

Enhanced antibacterial activity and osteoinductivity of Ag-loaded strontium hydroxyapatite/chitosan porous scaffolds for bone tissue engineering

Freeze-dried multiscale porous nanofibrous three dimensional scaffolds for bone regenerations.

Rapid mineralization of hierarchical poly(l-lactic acid)/poly(ε-caprolactone) nanofibrous scaffolds by electrodeposition for bone regeneration

Rapid mineralization of hierarchical poly(l-lactic acid)/poly(ε-caprolactone) nanofibrous scaffolds by electrodeposition for bone regeneration

Large three-dimensional poly(glycerol sebacate)-based scaffolds – a freeze-drying preparation approach

Hierarchically designed injectable hydrogel from oxidized dextran, amino gelatin and 4-arm poly(ethylene glycol)-acrylate for tissue engineering application

Synthesis of Porous Carbonate Apatite/Gelatin Scaffolds Via Freeze Drying Method

Bone Tissue Regeneration by Collagen Scaffolds with Different Calcium Phosphate Coatings: Amorphous Calcium Phosphate and Low-Crystalline Apatite

Rapid mineralization of porous gelatin scaffolds by electrodeposition for bone tissue engineering