NDLI: The assessment of biomarkers in sentinel cattle for monitoring vanadium exposure

Please wait, while we are loading the content...

NewsLegislationEnvironmental qualityChemical hazardsPublic & occupational healthResearch activities ( Journal of Environmental Monitoring Vol - 8 Issue - 4 )

Re-construction and updating our understanding on the global weapons tests ¹³⁷Cs fallout

Sequential element extraction of soils from abandoned farms: an investigation of the partitioning of anthropogenic element inputs from historic land use

The assessment of biomarkers in sentinel cattle for monitoring vanadium exposure

Passive sampling of herbicides combined with effect analysis in algae using a novel high-throughput phytotoxicity assay (Maxi-Imaging-PAM)

A comparison of European and North American atmospheric deposition networks: polycyclic aromatic hydrocarbons and lindane

Chemical markers of human waste contamination: Analysis of urobilin and pharmaceuticals in source waters

Local and regional air pollution in Ireland during an intensive aerosol measurement campaign

Comparison of pressurized fluid extraction, Soxhlet extraction and sonication for the determination of polycyclic aromatic hydrocarbons in urban air and diesel exhaust particulate matter

Back matter

Back cover

Journal of Environmental Monitoring Vol - 8 Issue - 3

Journal of Environmental Monitoring Vol - 8 Issue - 2

Journal of Environmental Monitoring Vol -7

Journal of Environmental Monitoring Vol -6

Journal of Environmental Monitoring Vol -5

Journal of Environmental Monitoring Vol -4

Journal of Environmental Monitoring Vol -3

Journal of Environmental Monitoring Vol -2

The assessment of biomarkers in sentinel cattle for monitoring vanadium exposure

Content Provider	Royal Society of Chemistry (RSC)
Author	Broek, J. den Gummow, B. Kirsten, W. F. A. Noordhuizen, J. P. T. M. Botha, C. J. Heesterbeek, J. A. P.
Copyright Year	2006
Abstract	Various potential biomarkers were sampled for vanadium every 3–4 months from Bos indicus beef cattle farmed extensively immediately adjacent (high exposure (HE) group) and two km away (low exposure (LE) group) from a vanadium processing plant, respectively. Vanadium intake (mg vanadium kg−1 bwt d−1) was modelled using environmental and physiological data as inputs. The vanadium intake ranged from 0.57 to 5.44 mg vanadium kg−1 bwt d−1 in the HE group and 0.41 to 2.61 mg vanadium kg−1 bwt d−1 in the LE group over a five-year period of monitoring. Samples collected from live sentinel animals over the five-year period included caudal coccygeal vertebrae, tail-switch hair, milk, urine, faeces, rib-bone biopsies and a wide range of blood clinical pathology and haematological parameters. The data was analysed for differences in response between the HE and LE groups. Where differences were found, a linear mixed-effects regression model was fitted to model the relationship between the exposure dose and the response variable. The model included the effects of age, duration of exposure and response, and allowed the prediction of the exposure dose given these inputs. Moreover, forty-two adult cattle were slaughtered over the five years. A wide range of tissue samples, rumen content and whole blood were taken from the cattle at slaughter for vanadium determination. In live animals, a difference in response was found between the HE group and LE group with respect to serum albumin (n = 36), monocyte (n = 36) and thrombocyte (n = 36) counts, and hair (n = 2) and faeces (n = 34) vanadium concentrations. No difference in vanadium concentrations could be shown for urine (n = 36), the traditional occupational health biomarker. Regression models are described for serum albumin, monocyte counts, faeces and hair, which showed the most promise as biomarkers. Average concentrations of vanadium in the tissues of slaughtered cattle ranged from 0.08 to 2.94 mg kg−1 (wet-weight basis) and rumen content contained 16.67 mg kg−1. Significant correlations were found between the exposure dose (end-dose) just prior to slaughter and the concentrations of vanadium in the coccygeal vertebrae, liver, diaphragm and rib-bone in descending order of magnitude. Other tissues showed poor correlation to the end-dose. Tissue levels of vanadium in healthy cattle include a much wider range than is currently reflected in the literature. The best tissue from slaughter animals for assessing chronic vanadium exposure is probably the liver.
Starting Page	445
Ending Page	455
Page Count	11
File Format	HTM / HTML PDF
ISSN	14640325
Volume Number	8
Issue Number	4
Journal	Journal of Environmental Monitoring
DOI	10.1039/b513860d
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Subscribed
Subject Keyword	Vanadium Zebu Coccyx Urine Clinical pathology Regression analysis Rumen Serum albumin Monocyte Platelet Biomarker Liver Thoracic diaphragm
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health Management, Monitoring, Policy and Law

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Assessment of workers’ exposure to palladium in a catalyst production plant

Determination of germanium in urine and its usefulness for biomonitoring of inhalation exposure to inorganic germanium in the occupational setting

Epigenetic Signatures as Biomarkers of Exposure

PAPER www.rsc.org/jem Journal of Environmental Monitoring The (2005)

Manganese air exposure assessment and biological monitoring in the manganese alloy production industry

Peracute vanadium toxicity in cattle grazing near a vanadium mine

Investigation of PAH Biomarkers in the Urine of Workers Exposed to Hot Asphalt

Blood manganese as an exposure biomarker: state of the evidence.

Biomonitoring and biomarkers: exposure assessment will never be the same.

The assessment of biomarkers in sentinel cattle for monitoring vanadium exposure

Similar Documents

Assessment of workers’ exposure to palladium in a catalyst production plant

Determination of germanium in urine and its usefulness for biomonitoring of inhalation exposure to inorganic germanium in the occupational setting

Epigenetic Signatures as Biomarkers of Exposure

PAPER www.rsc.org/jem Journal of Environmental Monitoring The (2005)

Manganese air exposure assessment and biological monitoring in the manganese alloy production industry

Peracute vanadium toxicity in cattle grazing near a vanadium mine

Investigation of PAH Biomarkers in the Urine of Workers Exposed to Hot Asphalt

Blood manganese as an exposure biomarker: state of the evidence.

Biomonitoring and biomarkers: exposure assessment will never be the same.

The assessment of biomarkers in sentinel cattle for monitoring vanadium exposure