NDLI: A novel macromolecular extract screened from satsuma with pro-inflammatory effect

Please wait, while we are loading the content...

Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan nutritional food Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells

Inhibitory effects of Momordica grosvenori Swingle extracts on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mouse skin

Enzyme-modified Panax ginseng inhibits UVB-induced skin aging through the regulation of procollagen type I and MMP-1 expression

A fucose containing polymer-rich fraction from the brown alga Ascophyllum nodosum mediates lifespan increase and thermal-tolerance in Caenorhabditis elegans, by differential effects on gene and protein expression

Photoprotection of human dermal fibroblasts against ultraviolet light by antioxidant combinations present in tomato

Efficient scavenging of β-carotene radical cations by antiinflammatory salicylates

A novel macromolecular extract screened from satsuma with pro-inflammatory effect

The antioxidant activity of soursop decreases the expression of a member of the NADPH oxidase family

The anti-inflammatory effect of a pomegranate husk extract on inflamed adipocytes and macrophages cultivated independently, but not on the inflammatory vicious cycle between adipocytes and macrophages

Enzyme-assisted extraction of κ/ι-hybrid carrageenan from Mastocarpus stellatus for obtaining bioactive ingredients and their application for edible active film development

The functional evaluation of waste yuzu (Citrus junos) seeds

Regulation effect of polysaccharides from Pleurotus tuber-regium (Fr.) on the immune activity of mice macrophages

Modulation of GSH with exogenous agents leads to changes in glyoxalase 1 enzyme activity in VL-17A cells exposed to chronic alcohol plus high glucose

Stability of creatine derivatives during simulated digestion in an in vitro model

Realistic intake of a flavanol-rich soluble cocoa product increases HDL-cholesterol without inducing anthropometric changes in healthy and moderately hypercholesterolemic subjects

Pasta supplemented with isolated lupin protein fractions reduces body weight gain and food intake of rats and decreases plasma glucose concentration upon glucose overload trial

Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells. A study on the mode of action

Effects of heme iron enriched peptide on iron deficiency anemia in rats

Back cover

Food & Function Vol -4

Food & Function Vol -3

Food & Function Vol -2

Food & Function Vol -1

A novel macromolecular extract screened from satsuma with pro-inflammatory effect

Content Provider	Royal Society of Chemistry (RSC)
Author	Ji, Qun Peng, Shu'ang Deng, Xiuxin Wu, Jinlong Yan, Huiqing Ma, Zhaocheng Chen, Doudou
Copyright Year	2014
Abstract	Excessive consumption of horticultural fruit is a double-edged sword with both positive and negative effects. In Eastern countries, a large number of people have suffered from shang huo as a result of excessive consumption of “heating” foods, such as lychee, longan, mandarin orange, mango and civet durian. The present study adopted a step by step strategy screened the compositions with pro-inflammatory effect in satsuma fruits. The pro-inflammatory effects of all fractions were evaluated in RAW 264.7 cell lines by enzyme-linked immunosorbent assay (ELISA) and RT-PCR tests. The soluble water extract (SWE) from satsuma increased the production of prostaglandin E2 (PGE2) and promoted the expression level of cyclooxygenase-2 (COX-2) mRNA. SWE and high molecular weight molecules extracted from soluble water extract (HSWE) were respectively fractionated by dialysis bags and gel filtration chromatography. The macromolecular fraction named F1 was further obtained from HSWE, and could increase the production of inflammatory mediators. Finally F1 was resolved by SDS-PAGE and six proteins were identified by mass spectrometry. Compared with other detected proteins, polygalacturonase inhibitor (PGIP) and chitinase were the most likely candidate pro-inflammatory proteins according to molecular mass, and both of them were Citrus unshiu species. cDNA sequences of PGIP and chitinase were cloned and their functions were predicted as defensive proteins by SMART analysis. Excessive intake of these defensive proteins may result in adverse food reactions in human beings, such as shang huo and other immune responses.
Starting Page	295
Ending Page	302
Page Count	8
File Format	HTM / HTML PDF
ISSN	20426496
Volume Number	5
Issue Number	2
Journal	Food & Function
DOI	10.1039/c3fo60411j
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	HSWE Lychee Longan Mandarin orange Mango Civet Durian Raw image format ELISA Reverse transcription polymerase chain reaction Sweden Prostaglandin Cyclooxygenase Prostaglandin-endoperoxide synthase 2 RNA Dialysis Chromatography Polyacrylamide gel electrophoresis Mass spectrometry Polygalacturonase Enzyme inhibitor Chitinase Molecular mass Citrus unshiu Complementary DNA
Content Type	Text
Resource Type	Article
Subject	Medicine Food Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Aroma Character Impact Compounds in Kinokuni Mandarin Orange (Citrus kinokuni) Compared with Satsuma Mandarin Orange (Citrus unshiu)

Different Phytohormonal Responses on Satsuma Mandarin (Citrus unshiu) Leaves Infected with Host-Compatible or Host-Incompatible Elsinoë fawcettii.

The Effect of Rootstocks on the Peel Phenolic Compounds of Satsuma mandarin (Citrus unshiu)

Citrus tristeza virus indexing and elimination from Satsuma mandarin (Citrus unshiu Marc.) cv. Kuno

Growth and fruiting behavoiur of satsuma mandarin citrus unshiu Marcovitch in relation to nitrogen nutrition

Hesperidin Accumulation during Fruit and Leaf Development in Satsuma Mandarin (Citrus unshiu)

Ethylene Production by Albedo Tissue of Satsuma Mandarin (Citrus unshiu Marc.) Fruit.

Green satsuma mandarin orange (Citrus unshiu) extract reduces adiposity and induces uncoupling protein expression in skeletal muscle of obese mice.

Increased CiFT abundance in the stem correlates with floral induction by low temperature in Satsuma mandarin (Citrus unshiu Marc.)

A novel macromolecular extract screened from satsuma with pro-inflammatory effect

Similar Documents

Aroma Character Impact Compounds in Kinokuni Mandarin Orange (Citrus kinokuni) Compared with Satsuma Mandarin Orange (Citrus unshiu)

Different Phytohormonal Responses on Satsuma Mandarin (Citrus unshiu) Leaves Infected with Host-Compatible or Host-Incompatible Elsinoë fawcettii.

The Effect of Rootstocks on the Peel Phenolic Compounds of Satsuma mandarin (Citrus unshiu)

Citrus tristeza virus indexing and elimination from Satsuma mandarin (Citrus unshiu Marc.) cv. Kuno

Growth and fruiting behavoiur of satsuma mandarin citrus unshiu Marcovitch in relation to nitrogen nutrition

Hesperidin Accumulation during Fruit and Leaf Development in Satsuma Mandarin (Citrus unshiu)

Ethylene Production by Albedo Tissue of Satsuma Mandarin (Citrus unshiu Marc.) Fruit.

Green satsuma mandarin orange (Citrus unshiu) extract reduces adiposity and induces uncoupling protein expression in skeletal muscle of obese mice.

Increased CiFT abundance in the stem correlates with floral induction by low temperature in Satsuma mandarin (Citrus unshiu Marc.)

A novel macromolecular extract screened from satsuma with pro-inflammatory effect