NDLI: A novel electrochemical sensor for non-ergoline dopamine agonist pramipexole based on electrochemically reduced graphene oxide nanoribbons

Content Provider	Royal Society of Chemistry (RSC)
Author	Seetharamappa, J. Narayana, Prashanth S. Satpati, Ashis K. Teradal, Nagappa L.
Copyright Year	2015
Abstract	A facile and feasible electrochemical sensing platform based on electrochemically reduced graphene oxide nanoribbons (ERGONRs) was designed for electrochemical investigations and determination of a non-ergoline dopamine agonist, pramipexole dihydrochloride monohydrate (PPX), in pharmaceutical formulations and biological fluids. Newly synthesized graphene oxide nanoribbons were characterized by SEM, AFM, XRD and EDX. The solution of graphene oxide nanoribbons (GONRs) was placed on a glassy carbon electrode (GCE) and reduced electrochemically in phosphate buffer solution of pH 6 to obtain the electrochemically reduced graphene oxide nanoribbon modified glassy carbon electrode (ERGONR-GCE). Significant electrooxidation of PPX was observed at the ERGONR-GCE in phosphate buffer of pH 6.0 compared to that at the bare GCE. The effect of accumulation time, pH and scan rate was studied and various electrochemical parameters were evaluated. The plot of pH versus Ep yielded a slope of 57.65 mV per pH in the pH range of 3.0–8.0 indicating the participation of an equal number of electrons and protons in the electrode process. A differential pulse voltammetric method was developed for the determination of PPX in bulk, pharmaceutical formulations and urine samples. PPX showed a linear relationship between the peak current and the concentration in the range of 0.01–15 μM with a LOD of 2.8 nM and a LOQ of 9.4 nM. The fabricated electrode also showed good selectivity and excellent sensitivity. The proposed method is simple, rapid and inexpensive and hence could be readily adopted for the analysis of PPX. The results were subjected to statistical analysis.
Starting Page	3912
Ending Page	3919
Page Count	8
File Format	HTM / HTML PDF
ISSN	17599660
Volume Number	7
Issue Number	9
Journal	Analytical Methods
DOI	10.1039/c5ay00282f
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	X-ray crystallography Urine Electrode Graphene Phosphate Dopamine agonist Electrochemistry PH Buffer solution Carbon Pramipexole Graphene nanoribbons
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry Engineering Chemical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

A voltammetric sensor based on electrochemically reduced graphene modified electrode for sensitive determination of midecamycin

Highly sensitive electrochemical sensor for dopamine with a double-stranded deoxyribonucleic acid/gold nanoparticle/graphene modified electrode

Electro-reduced graphene oxide film modified glassy carbon electrode as an electrochemical sensor for sibutramine

Improved Electrochemical Detection of Zinc Ions Using Electrode Modified with Electrochemically Reduced Graphene Oxide

Dopamine sensor based on a glassy carbon electrode modified with a reduced graphene oxide and palladium nanoparticles composite

Fabrication of Amine-Modified Magnetite-Electrochemically Reduced Graphene Oxide Nanocomposite Modified Glassy Carbon Electrode for Sensitive Dopamine Determination

Electrochemical behavior of isofraxidin at an electrodeposition reduced graphene oxide electrode and its analytical application

A facile sensitive l-tyrosine electrochemical sensor based on a coupled CuO/Cu₂O nanoparticles and multi-walled carbon nanotubes nanocomposite film

Glassy Carbon Electrode Modified with N-Doped Reduced Graphene Oxide Sheets as an Effective Electrochemical Sensor for Amaranth Detection

A novel electrochemical sensor for non-ergoline dopamine agonist pramipexole based on electrochemically reduced graphene oxide nanoribbons

Similar Documents

A voltammetric sensor based on electrochemically reduced graphene modified electrode for sensitive determination of midecamycin

Highly sensitive electrochemical sensor for dopamine with a double-stranded deoxyribonucleic acid/gold nanoparticle/graphene modified electrode

Electro-reduced graphene oxide film modified glassy carbon electrode as an electrochemical sensor for sibutramine

Improved Electrochemical Detection of Zinc Ions Using Electrode Modified with Electrochemically Reduced Graphene Oxide

Dopamine sensor based on a glassy carbon electrode modified with a reduced graphene oxide and palladium nanoparticles composite

Fabrication of Amine-Modified Magnetite-Electrochemically Reduced Graphene Oxide Nanocomposite Modified Glassy Carbon Electrode for Sensitive Dopamine Determination

Electrochemical behavior of isofraxidin at an electrodeposition reduced graphene oxide electrode and its analytical application

A facile sensitive l-tyrosine electrochemical sensor based on a coupled CuO/Cu2O nanoparticles and multi-walled carbon nanotubes nanocomposite film

Glassy Carbon Electrode Modified with N-Doped Reduced Graphene Oxide Sheets as an Effective Electrochemical Sensor for Amaranth Detection

A novel electrochemical sensor for non-ergoline dopamine agonist pramipexole based on electrochemically reduced graphene oxide nanoribbons

A facile sensitive l-tyrosine electrochemical sensor based on a coupled CuO/Cu₂O nanoparticles and multi-walled carbon nanotubes nanocomposite film