NDLI: A label-free electrochemical aptasensor based on leaf-like vanadium disulfide-Au nanoparticles for the sensitive and selective detection of platelet-derived growth factor BB

Content Provider	Royal Society of Chemistry (RSC)
Author	Liu, Xue Shuai, Hong-Lei Huang, Ke-Jing
Copyright Year	2015
Abstract	In this work, an electrochemical aptasensor for the sensitive detection of platelet-derived growth factor BB (PDGF-BB) is fabricated based on leaf-like VS2 nanosheets which are prepared by a facile hydrothermal method. The scanning electron microscopy and transmission electron microscopy images demonstrate that the as-prepared VS2 is constructed with many irregular sheets in a leaf-like structure with a thickness of several nanometers. The electrochemical aptasensor is constructed by depositing Au nanoparticles (AuNPs) on the VS2 nanosheet modified glassy carbon electrode and then immobilizing the aptamer. Using the AuNP/VS2 composite as the sensing platform greatly enhances the effective surface area of the electrode and thus amplifying the detection response. The proposed aptasensor can sensitively detect PDGF-BB with a low detection limit of 0.4 pM and over a wide target concentration range of 0.001 nM to 1.0 nM. The aptasensor has been successfully applied in the determination of PDGF-BB in human urine samples and the results compared well with those by the reference ELISA method, indicating its promise in biochemical analysis.
Starting Page	8277
Ending Page	8284
Page Count	8
File Format	HTM / HTML PDF
ISSN	17599660
Volume Number	7
Issue Number	19
Journal	Analytical Methods
DOI	10.1039/c5ay01793a
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Urine Transmission electron microscopy Nanosheet Electrode Hydrothermal circulation Electrochemistry Aptamer Scanning electron microscope Carbon Growth factor
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry Engineering Chemical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

An aptamer electrochemical assay for sensitive detection of immunoglobulin E based on tungsten disulfide–graphene composites and gold nanoparticles

A novel aptamer sensor based on layered tungsten disulfide nanosheets and Au nanoparticles amplification for 17β-estradiol detection

A highly sensitive electrochemical OP biosensor based on electrodeposition of Au–Pd bimetallic nanoparticles onto a functionalized graphene modified glassy carbon electrode

Au NPs–Ni(OH)₂–Cu nanocomposites enhanced electrochemical properties for detection of H₂O₂

An electrochemical sensor based on a magnetic Fe₃O₄ nanoparticles and gold nanoparticles modified electrode for sensitive determination of trace amounts of arsenic(iii)

A new portable toluidine blue/aptamer complex-on-polyethyleneimine-coated gold nanoparticles-based sensor for label-free electrochemical detection of alpha-fetoprotein

Sensitive electrochemical determination of promethazine hydrochloride based on the poly(p-aminobenzene sulfonic acid)/flowerlike ZnO crystals composite film

Hydrothermal preparation of WO₃ nanorod array and ZnO nanosheet array composite structures on FTO substrates with enhanced photocatalytic properties

A novel sensitive and selective electrochemical sensor based on molecularly imprinted polymer on a nanoporous gold leaf modified electrode for warfarin sodium determination

A label-free electrochemical aptasensor based on leaf-like vanadium disulfide-Au nanoparticles for the sensitive and selective detection of platelet-derived growth factor BB

Similar Documents

An aptamer electrochemical assay for sensitive detection of immunoglobulin E based on tungsten disulfide–graphene composites and gold nanoparticles

A novel aptamer sensor based on layered tungsten disulfide nanosheets and Au nanoparticles amplification for 17β-estradiol detection

A highly sensitive electrochemical OP biosensor based on electrodeposition of Au–Pd bimetallic nanoparticles onto a functionalized graphene modified glassy carbon electrode

Au NPs–Ni(OH)2–Cu nanocomposites enhanced electrochemical properties for detection of H2O2

An electrochemical sensor based on a magnetic Fe3O4 nanoparticles and gold nanoparticles modified electrode for sensitive determination of trace amounts of arsenic(iii)

A new portable toluidine blue/aptamer complex-on-polyethyleneimine-coated gold nanoparticles-based sensor for label-free electrochemical detection of alpha-fetoprotein

Sensitive electrochemical determination of promethazine hydrochloride based on the poly(p-aminobenzene sulfonic acid)/flowerlike ZnO crystals composite film

Hydrothermal preparation of WO3 nanorod array and ZnO nanosheet array composite structures on FTO substrates with enhanced photocatalytic properties

A novel sensitive and selective electrochemical sensor based on molecularly imprinted polymer on a nanoporous gold leaf modified electrode for warfarin sodium determination

A label-free electrochemical aptasensor based on leaf-like vanadium disulfide-Au nanoparticles for the sensitive and selective detection of platelet-derived growth factor BB

Au NPs–Ni(OH)₂–Cu nanocomposites enhanced electrochemical properties for detection of H₂O₂

An electrochemical sensor based on a magnetic Fe₃O₄ nanoparticles and gold nanoparticles modified electrode for sensitive determination of trace amounts of arsenic(iii)

Hydrothermal preparation of WO₃ nanorod array and ZnO nanosheet array composite structures on FTO substrates with enhanced photocatalytic properties