NDLI: A system for the continuous generation of simulated human breath supplemented with trace gases

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Analytical Methods Vol - 4 Issue - 6

Analytical Methods Vol - 4 Issue - 5

Analytical Methods Vol - 4 Issue - 4

Analytical Methods Vol - 4 Issue - 3

Analytical Methods Vol - 4 Issue - 2

Analytical Methods Vol -3

Analytical Methods Vol -2

Analytical Methods Vol -1

A system for the continuous generation of simulated human breath supplemented with trace gases

Content Provider	Royal Society of Chemistry (RSC)
Author	Shahbazian, Zahra Killard, Anthony J. Crowley, Karl Hibbard, Troy
Copyright Year	2012
Abstract	A system was developed to simulate the relative humidity (RH) and temperature characteristics of human breath at a constant human volume flow rate. The system was also designed to allow supplementation of the artificial breath with known concentrations of a trace gas; in this case, ammonia. The system was assembled from several components including an air pump, respiratory humidifier, mass flow controllers and additional valves and sensors to monitor and verify the system variables. Flow rates were measured as maximum voluntary ventilation (MVV) and could be set to standards within human levels. The desired temperature (i.e. 32 to 37 °C) and relative humidity (i.e. 91 to 96%) ranges could be achieved over defined operational periods. Good agreement for the concentration of ammonia in the simulated breath matrix was obtained between the theoretically calculated concentration and with photoacoustic spectroscopy in the clinically relevant range of 18 to 2993 ppb (r2 = 0.9978). The system can be used for the calibration of sensors being developed for breath monitoring applications.
Starting Page	2172
Ending Page	2176
Page Count	5
File Format	HTM / HTML PDF
ISSN	17599660
Volume Number	4
Issue Number	7
Journal	Analytical Methods
DOI	10.1039/c2ay25195g
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Relative humidity Ammonia MVV Maastricht Humidifier Positive-definite matrix Photoacoustic spectroscopy
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry Engineering Chemical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
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