NDLI: High Prevalence of TT Virus Infection in Healthy Children and Adults and in Patients with Liver Disease in Taiwan

Content Provider	PubMed Central
Author	Hsieh, Sen-yung Wu, Yin-hua Ho, Yu-pin Tsao, Kuo-chien Yeh, Chau-ting Liaw, Yun-fan
Copyright Year	1999
Abstract	A newly identified DNA virus, named TT virus (TTV), was found to be related to transfusion-associated hepatitis. We conducted the following experiments to evaluate its pathogenic role in liver disease and potential modes of transmission. We used PCR to detect TTV DNA in serum. The rates of TTV viremia in 13 patients with idiopathic acute hepatitis, 14 patients with idiopathic fulminant hepatitis, 22 patients with chronic hepatitis, and 19 patients with cirrhosis of the liver were 46, 64, 55, and 63%, respectively, and were not significantly different from those in 50 healthy control subjects (53%). PCR products derived from seven patients with liver disease and three healthy controls were cloned and then subjected to phylogenetic analyses, which failed to link a virulent strain of TTV to severe liver disease. TTV infection was further assessed in an additional 148 subjects with normal liver biochemical tests, including 30 newborns (sera collected from the umbilical cord), 23 infants, 16 preschool children, 21 individuals of an age prior to that of sexual experience (aged 6 to 15 years), 15 young adults (aged under 30 years), and 43 individuals older than 30 years. The rates of TTV viremia were 0, 17, 25, 33, 47, and 54%, respectively. These findings suggest that TTV is transmitted mainly via nonparenteral daily contact and frequently occurs very early in life and that TTV infection does not have a significant effect on liver disease.
Starting Page	1829
File Format	PDF
ISSN	1098660X
e-ISSN	1098660X
Journal	Journal of Clinical Microbiology
Issue Number	6
Volume Number	37
Language	English
Publisher	American Society for Microbiology
Publisher Date	1999-06-01
Access Restriction	Open
Rights Holder	American Society for Microbiology
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Microbiology (medical)

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

TT virus infection in children and adults who visited a general hospital in the south of Brazil for routine procedure

The prevalence of TT virus and GB virus C/hepatitis G virus infection in individuals with raised liver enzymes but without HBV or HCV infection in Taiwan.

High prevalence of Borna disease virus infection in healthy sheep in Japan.

Prevalence and implication of TT virus infection: Minimal role in patients with non-A-E hepatitis in Taiwan

High Prevalence of TT Virus (TTV) and TTV-Like Minivirus in Cervical Swabs

High Prevalence of TT Virus DNA in Human Saliva and Semen

High incidence of hepatitis C virus infection in hemodialysis patients in units with high prevalence.

Coinfection with Multiple TT Virus Strains Belonging to Different Genotypes Is a Common Event in Healthy Brazilian Adults

TT virus infection in children and adults who visited a general hospital in the south of Brazil for routine procedure

High Prevalence of TT Virus Infection in Healthy Children and Adults and in Patients with Liver Disease in Taiwan

Similar Documents

TT virus infection in children and adults who visited a general hospital in the south of Brazil for routine procedure

The prevalence of TT virus and GB virus C/hepatitis G virus infection in individuals with raised liver enzymes but without HBV or HCV infection in Taiwan.

High prevalence of Borna disease virus infection in healthy sheep in Japan.

Prevalence and implication of TT virus infection: Minimal role in patients with non-A-E hepatitis in Taiwan

High Prevalence of TT Virus (TTV) and TTV-Like Minivirus in Cervical Swabs

High Prevalence of TT Virus DNA in Human Saliva and Semen

High incidence of hepatitis C virus infection in hemodialysis patients in units with high prevalence.

Coinfection with Multiple TT Virus Strains Belonging to Different Genotypes Is a Common Event in Healthy Brazilian Adults

TT virus infection in children and adults who visited a general hospital in the south of Brazil for routine procedure

High Prevalence of TT Virus Infection in Healthy Children and Adults and in Patients with Liver Disease in Taiwan