NDLI: Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter.

Please wait, while we are loading the content...

Year: 2016, Volume: 35

Year: 2015, Volume: 34

Year: 2014, Volume: 33

Year: 2013, Volume: 33

Year: 2013, Volume: 32

Year: 2012, Volume: 32

Year: 2012, Volume: 31

Year: 2011, Volume: 30

Year: 2010, Volume: 29

Year: 2009, Volume: 28

Year: 2008, Volume: 27

Year: 2007, Volume: 26

Year: 2006, Volume: 26

Year: 2006, Volume: 25

Year: 2005, Volume: 24

Year: 2004, Volume: 24

Year: 2004, Volume: 23

Year: 2003, Volume: 22

Year: 2002, Volume: 21

Year: 2001, Volume: 20

Year: 2000, Volume: 19

Year: 1999, Volume: 18

Year: 1998, Volume: 17

Year: 1997, Volume: 16

Year: 1996, Volume: 15

Year: 1995, Volume: 14

Year: 1994, Volume: 13

Year: 1993, Volume: 12

Year: 1992, Volume: 11

Year: 1991, Volume: 10

Year: 1990, Volume: 9

Year: 1989, Volume: 8

Year: 1988, Volume: 7

Year: 1987, Volume: 6

Year: 1987, Volume: 6, Issue: 13

Cin4, an insert altering the structure of the A1 gene in Zea mays, exhibits properties of nonviral retrotransposons

Studies on the introduction and mobility of the maize Activator element in Arabidopsis thaliana and Daucus carota.

Independent and synergistic activity of rol A, B and C loci in stimulating abnormal growth in plants

GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants.

Three dimensional structure of porcine pancreatic alpha-amylase at 2.9 A resolution. Role of calcium in structure and activity.

Differential expression of nicotinic acetylcholine receptor genes in innervated and denervated chicken muscle.

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

The primary structure of human dopamine-beta-hydroxylase: insights into the relationship between the soluble and the membrane-bound forms of the enzyme.

Specific phosphorylation of proteins in pore complex-laminae from the sponge Geodia cydonium by the homologous aggregation factor and phorbol ester. Role of protein kinase C in the phosphorylation of DNA topoisomerase II.

Purification of a novel, nucleoplasmin-like protein from somatic nuclei.

Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells.

Calmodulin is involved in regulation of cell proliferation.

Regulation of membrane IgM expression in secretory B cells: translational and post-translational events.

Interleukin 3-specific tyrosine phosphorylation of a membrane glycoprotein of Mr 150,000 in multi-factor-dependent myeloid cell lines.

The chicken progesterone receptor: sequence, expression and functional analysis.

Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF).

Monoclonal antibodies to the insulin receptor stimulate the intrinsic tyrosine kinase activity by cross-linking receptor molecules.

Acute regulation of insulin-like growth factor-I gene expression by growth hormone during adipose cell differentiation.

Inducible and tissue-specific expression of human C-reactive protein in transgenic mice.

cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.

The sequence of rat leukosialin (W3/13 antigen) reveals a molecule with O-linked glycosylation of one third of its extracellular amino acids.

Alternative internal splicing in c-myb RNAs occurs commonly in normal and tumor cells.

Molecular characterization of the testis specific c-abl mRNA in mouse.

The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse cDNA clones highly homologous to the yeast YPT1 gene.

Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice.

In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter.

Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter.

A Xenopus laevis gene encodes both homeobox-containing and homeobox-less transcripts.

Developmental expression of a regulatory gene is programmed at the level of splicing.

Evidence that a regulatory gene autoregulates splicing of its transcript.

Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster

KP elements repress P-induced hybrid dysgenesis in Drosophila melanogaster.

A naturally occurring gene encoding the major surface antigen precursor p190 of Plasmodium falciparum lacks tripeptide repeats.

Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein.

The F-actin capping proteins of Physarum polycephalum: cap42(a) is very similar, if not identical, to fragmin and is structurally and functionally very homologous to gelsolin; cap42(b) is Physarum actin.

Cleavage and polyadenylation of messenger RNA precursors in vitro occurs within large and specific 3' processing complexes.

A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA.

Analysis of mRNA 3' end formation by modification interference: the only modifications which prevent processing lie in AAUAAA and the poly(A) site.

Specific pre-cleavage and post-cleavage complexes involved in the formation of SV40 late mRNA 3' termini in vitro.

Thyroperoxidase, an auto-antigen with a mosaic structure made of nuclear and mitochondrial gene modules.

Preferential recombination between GC clusters in yeast mitochondrial DNA.

Antagonistic controls regulate copy number of the yeast 2 mu plasmid.

DNA methylation can enhance or induce DNA curvature.

Structural and functional relationships between prokaryotic and eukaryotic DNA polymerases.

A new target for CRP action at the malT promoter.

Mutants of elongation factor Tu promote ribosomal frameshifting and nonsense readthrough.

Organization of the murine Ig-related λ5 gene transcribed selectively in pre-B lymphocytes

Year: 1987, Volume: 6, Issue: 12

Year: 1987, Volume: 6, Issue: 11

Year: 1987, Volume: 6, Issue: 10

Year: 1987, Volume: 6, Issue: 9

Year: 1987, Volume: 6, Issue: 8

Year: 1987, Volume: 6, Issue: 7

Year: 1987, Volume: 6, Issue: 6

Year: 1987, Volume: 6, Issue: 5

Year: 1987, Volume: 6, Issue: 4

Year: 1987, Volume: 6, Issue: 3

Year: 1987, Volume: 6, Issue: 2

Year: 1987, Volume: 6, Issue: 1

Year: 1986, Volume: 5

Year: 1985, Volume: 4

Year: 1984, Volume: 3

Year: 1983, Volume: 2

Year: 1982, Volume: 1

Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter.

Content Provider	PubMed Central
Author	Raychaudhuri, P. Rooney, R. Nevins, J. R.
Abstract	We have previously shown that E1A-mediated induction of the adenovirus E2 transcription unit likely involves the posttranslational activation of a previously limiting cellular factor termed E2F. However, this factor is not involved in E1A induction of several other viral genes, including the E4 gene, since it does not bind to the promoters of these genes. We have undertaken an analysis of proteins which bind to the E4 promoter in an attempt to define the basis for E1A control of this gene. Gel retardation binding assays revealed a large number of interactions with the E4 promoter consistent with the fact that at least 180 nucleotides of sequence are required for full promoter activity. The analysis was simplified by employing small probes as well as by using partially fractionated extracts. By so doing, we have identified at least seven discrete factor interactions involving the E4 promotor. Multiple interactions, as defined by discrete gel complexes, were identified with a site previously shown to be critical for promoter activity as well as E1A control. We find that one of these factors, termed E4F, is increased at least 10-fold in extracts prepared from Ad5 infected cells and that the increase requires the E1A gene. Furthermore, the activation is maximal by 3 h post-infection, consistent with the kinetics of activation of E4 transcription. Competition binding assays demonstrated that the E4F factor was E4 specific and did not interact with any other E1A inducible promoter. We therefore conclude that the induced E4F factor is likely responsible for the E1A-induced transcription of E4, thereby suggesting that E1A control must involve an activation of multiple promoter specific binding proteins.
Starting Page	4073
File Format	PDF
ISSN	14602075
e-ISSN	14602075
Journal	The EMBO Journal
Issue Number	13
Volume Number	6
Language	English
Publisher Date	1987-12-20
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Neuroscience Immunology and Microbiology Medicine Molecular Biology

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in