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| Content Provider | PubMed Central |
|---|---|
| Author | Yoshioka, Yuichiro Nozawa, Hiroaki Tanaka, Junichiro Nishikawa, Takeshi Tanaka, Toshiaki Kiyomatsu, Tomomichi Kawai, Kazushige Hata, Keisuke Kazama, Shinsuke Yamaguchi, Hironori Ishihara, Soichiro Sunami, Eiji Kitayama, Joji Watanabe, Toshiaki |
| Copyright Year | 2016 |
| Abstract | Patients with hereditary hemorrhagic telangiectasia (HHT) are reportedly at a lower overall risk of malignancies, and small bowel adenocarcinoma (SBA) arising in a HHT patient is extremely rare. In this study, the case of a 37-year-old female with HHT who developed a poorly differentiated jejunal adenocarcinoma five years after ileocecal resection for multiple colonic adenomas is presented. The patient underwent curative resection of the cancer invading the ileum and the mesentery of the transverse colon, but had to overcome critical complications perioperatively, stemming from HHT-associated peripheral capillary dilatation and arteriovenous malformation, including nosebleeds and possible infusion-induced air embolism through pulmonary shunts. The patient subsequently received adjuvant chemotherapy including capecitabine and oxaliplatin for 6 months, and currently remains alive without any evidence of recurrence 12 months after the second surgery. This patient with SBA was an instructive case demonstrating the necessity of careful attention during major surgery in HHT. |
| Related Links | http://dx.doi.org/10.3892/ol.2016.4173 |
| Ending Page | 2139 |
| Page Count | 3 |
| Starting Page | 2137 |
| File Format | |
| ISSN | 17921074 |
| e-ISSN | 17921082 |
| Journal | Oncology Letters |
| Issue Number | 3 |
| Volume Number | 11 |
| Language | English |
| Publisher | D.A. Spandidos |
| Publisher Date | 2016-02-01 |
| Access Restriction | Open |
| Rights Holder | D.A. Spandidos |
| Subject Keyword | Cancer Research Oncology Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cancer Research Oncology |
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