NDLI: Interim analysis for binary outcome trials with a long fixed follow-up time and repeated outcome assessments at pre-specified times

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Year: 2016, Volume: 5

Year: 2015, Volume: 4

Year: 2014, Volume: 3

Year: 2014, Volume: 3, Issue: Unspecified

Immortalized tumor derived rat fibroblasts as feeder cells facilitate the cultivation of male embryonic stem cells from the rat strain WKY/Ztm

The surprising influence of family history to type 2 diabetes on anaerobic performance of young male élite athletes

Herpes simplex encephalitis in Iceland 1987–2011

Extraction and characterization of keratin from bovine hoof: A potential material for biomedical applications

Phylogenetic analysis of newly isolated grass carp reovirus

Human kallikrein-2 gene and protein expression predicts prostate cancer at repeat biopsy

Therapeutic impact of organism isolation in management of patients with pyogenic vertebral osteomyelitis

Chat (Catha edulis): a socio economic crop in Harar Region, Eastern Ethiopia

HCC surveillance results in earlier HCC detection: results from an Indian cohort

The sheep KAP8-2 gene, a new KAP8 family member that is absent in humans

Detection of alterations in membrane metabolism during neoadjuvant chemotherapy in patients with breast cancer using phosphorus magnetic resonance spectroscopy at 7 Tesla

Leptin receptor polymorphism Gln223Arg (rs1137101) in oral squamous cell carcinoma and potentially malignant oral lesions

Identification of nucleotide sequence involved in Weissellicin L production

Novel uterine sarcoma preoperative diagnosis score predicts the need for surgery in patients presenting with a uterine mass

An investigation of trauma-associated appraisals and posttraumatic stress disorder in British and Asian trauma survivors: the development of the Public and Communal Self Appraisals Measure (PCSAM)

A structured approach to design-for-frequency problems using the Cayley-Hamilton theorem

TPS1 drug design for rice blast disease in magnaporthe oryzae

Viewing systematic reviews and meta-analysis in social research through different lenses

Design of a reversible single precision floating point subtractor

Leading across cultures in the human age: an empirical investigation of intercultural competency among global leaders

A novel low-complexity post-processing algorithm for precise QRS localization

Comments on the mechanisms of action of radiation protective agents: basis components and their polyvalence

Direct application of Padé approximant for solving nonlinear differential equations

Geophysical assessments of renewable gas energy compressed in geologic pore storage reservoirs

Dothideomycetes and Leotiomycetes sterile mycelia isolated from the Italian seagrass Posidonia oceanica based on rDNA data

Identification of sample donor by 24-plex short tandem repeat in a post-race equine plasma containing dexamethasone

Factors affecting branch failures in open-grown trees during a snowstorm in Massachusetts, USA

Methods and protocol of a mixed method quasi-experiment to evaluate the effects of a structural economic and food security intervention on HIV vulnerability in rural Malawi: The SAGE4Health Study

Situs inversus totalis with congenitally corrected transposition of the great arteries: insights from cardiac MRI

Concentrations of strontium, barium, cadmium, copper, zinc, manganese, chromium, antimony, selenium and lead in the equine liver and kidneys

Intracranial hypotension after trauma

Proximate composition, mineral content and antinutritional factors of Brebra (Millettia ferruginea) seed flour as well as physicochemical characterization of its seed oil

Erratum to: El Nino Southern Oscillation (ENSO) impact on tuna fisheries in Indian Ocean

Spatial analysis of cattle and shoat population in Ethiopia: growth trend, distribution and market access

Will women soon outperform men in open-water ultra-distance swimming in the ‘Maratona del Golfo Capri-Napoli’?

Laparoscopic patch repair of recurrent anterior diaphragmatic hernia in a child with SMA

Pcf1, a large subunit of CAF-1, required for maintenance of checkpoint kinase Cds1 activity

Integrated analysis of chronic lipotoxicity on muscle metabolism and stress and its reversal by antioxidants

A PCR method for VKORC1 G-1639A and CYP2C9 A1075C genotyping useful to warfarin therapy among Japanese

Simple clinical indicators for early psoriatic arthritis detection

Effect of ambient storage on the quality characteristics of aerobically packaged fish curls incorporated with different flours

Do we protect freshwater eels or do we drive them to extinction?

HAV in fresh vegetables: a hidden health risk in district Mardan, Pakistan

UV/Visible spectra of a series of natural and synthesised anthraquinones: experimental and quantum chemical approaches

The effect of standing and sitting postures on breathing in brass players

Concomitant use of tamoxifen and endoxifen in postmenopausal early breast cancer: prediction of plasma levels by physiologically-based pharmacokinetic modeling

Individually wide range of renal motion evaluated by four-dimensional computed tomography

Analysis of tennis champions’ career: how did top-ranked players perform the previous years?

Persistent left superior vena cava detected after central venous catheter insertion

Overstimulation can create health problems due to increases in PI3K/Akt/GSK3 insensitivity and GSK3 activity

Study protocol of the Going to Stay at Home program: evaluation of a residential carer training program to reduce dementia carer distress and burden

Illness perception in tuberculosis by implementation of the Brief Illness Perception Questionnaire – a TBNET study

Grain iron and zinc density in pearl millet: combining ability, heterosis and association with grain yield and grain size

Porosity and dielectric properties as tools to predict drug release trends from hydrogels

Driving for patients in palliative care–a reality?

Lung cancer: a 6-field technique using lateral beams in conformal radiotherapy for bilateral supraclavicular lymph node metastases

Cardiac taurine and principal amino acids in right and left ventricles of patients with either aortic valve stenosis or coronary artery disease: the importance of diabetes and gender

Association of hypertension with coronary artery disease onset in the Lebanese population

Liquid film condensation along a vertical surface in a thin porous medium with large anisotropic permeability

Necrotizing fasciitis as a rare complication of osteonecrosis of the jaw in a patient with multiple myeloma treated with lenalidomide: case report and review of the literature

Tiger density in a tropical lowland forest in the Eastern Himalayan Mountains

Mitigating role of thymoquinone rich fractions from Nigella sativa oil and its constituents, thymoquinone and limonene on lipidemic-oxidative injury in rats

Diagnostic challenge of paroxysmal sympathetic hyperactivity (PSH) associated with diffuse axonal injury (DAI) in head trauma

Reproductive biology and genetic diversity of the green turtle (Chelonia mydas) in Vamizi island, Mozambique

Genetic analysis of resistance to Pseudomonas syringae pv. actinidiae (Psa) in a kiwifruit progeny test: an application of generalised linear mixed models (GLMMs)

Identification of novel glycosyl hydrolases with cellulolytic activity against crystalline cellulose from metagenomic libraries constructed from bacterial enrichment cultures

Increased cardiovascular risk factors in breast cancer survivors identified by routine measurements of body composition, resting heart rate and arterial blood pressure

Comparison between leached metakaolin and leached diatomaceous earth as raw materials for the synthesis of ZSM-5

LAP degradation product reflects plasma kallikrein-dependent TGF-β activation in patients with hepatic fibrosis

Higher order temporal finite element methods through mixed formalisms

A case of post-transplant adult T-cell leukemia/lymphoma presenting myelopathy similar to but distinct from human T-cell leukemia virus type I (HTLV- I)-associated myelopathy

Groundwater contamination in Ibadan, South-West Nigeria

Microbiological profiling and the demonstration of in vitro anti-bacterial traits of the major oral herbal medicines used in Dhaka Metropolis

Sequence of inequalities among fuzzy mean difference divergence measures and their applications

Severe experimental folate deficiency in a human subject - a longitudinal investigation of red-cell folate immunoassay errors as megaloblastic anaemia develops

Rich and purposeful mathematical knowledge of mothers and children in a Torres Strait Islander community

On the average temperature of airless spherical bodies and the magnitude of Earth’s atmospheric thermal effect

Endovascular repair of aortic dissection and intramural hematoma: indications and serial changes

Sex differences in cardiovascular function during submaximal exercise in humans

Life threatening illness in popular movies-a first descriptive analysis

Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine

Multivariate statistical models of metabolomic data reveals different metabolite distribution patterns in isonitrosoacetophenone-elicited Nicotiana tabacum and Sorghum bicolor cells

Girls Just Wanna Have Fun: a process evaluation of a female youth-driven physical activity-based life skills program

Effect of dietary coenzyme Q10 supplementation on the growth rate, carcass characters and cost effectiveness of broiler fed with three energy levels

Routines for reducing the occurrence of emergence agitation during awakening in children, a national survey

Invasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptor

Practice of switch from intravenous to oral antibiotics

Mean-field analysis of orientation selectivity in inhibition-dominated networks of spiking neurons

Symptomatic loosening of a total knee arthroplasty caused by a tibial chondrosarcoma – a case report

Expression of a manganese peroxidase isozyme 2 transgene in the ethanologenic white rot fungus Phlebia sp. strain MG-60

Effects of pressure angle and tip relief on the life of speed increasing gearbox: a case study

Comparison of in vitro acaricidal effects of commercial preparations of cypermethrin and fenvalerate against Rhipicephalus (Boophilus) annulatus

Potential statin-drug interactions: prevalence and clinical significance

Bayesian hierarchical spatial regression of maternal depressive symptoms in South Western Sydney, Australia

Primary mediastinal goiters

Robotic 3D scanner as an alternative to standard modalities of medical imaging

Pectoral nerves (PECS) and intercostal nerve block for cardiac resynchronization therapy device implantation

A review of the evolution and trajectory of the African union as an instrument of regional integration

Adenomyoma of the small intestine a rare pathological lead point for intussusception in an infant

A randomized controlled trial to evaluate an educational strategy involving community health volunteers in improving self-care in patients with chronic heart failure: Rationale, design and methodology

New extended (G’/G)-expansion method to solve nonlinear evolution equation: the (3 + 1)-dimensional potential-YTSF equation

Saudi high school students’ attitudes and barriers toward the use of computer technologies in learning English

Relationship between humoral response against hepatitis C virus and disease overcome

New Zealand consumers’ perceptions of private insurance for pharmaceuticals

Vertex collocation profiles: theory, computation, and results

In the right order of brush strokes: a sketch of a software philosophy retrospective

Stem cells in a three-dimensional scaffold environment

Response to imatinib as a function of target kinase expression in recurrent glioblastoma

Effects of follicular versus luteal phase-based strength training in young women

Exploring the economic and social effects of care dependence in later life: protocol for the 10/66 research group INDEP study

PTSD symptoms as a consequence of breast cancer diagnosis: clinical implications

Acceptability and willingness among men who have sex with men (MSM) to use a tablet-based HIV risk assessment in a clinical setting

Successive exposure to moderate hypoxia does not affect glucose metabolism and substrate oxidation in young healthy men

Co-morbidity and predictors of health status in older rural breast cancer survivors

The dependency of compound biological effectiveness factors on the type and the concentration of administered neutron capture agents in boron neutron capture therapy

Donor-derived 47, XXY in an unrelated cord blood transplant recipient

Stem cell therapy for cardiac dysfunction

Unusual markedly-dilated chorionic vessels with placentomegaly

Sergei Prokofiev’s Children’s Pieces, Op. 65: a comprehensive approach to learning about a composer and his works: biography, style, form and analysis

Calibration of an automated California mastitis test with focus on the device-dependent variation

Tumor grade of clear cell renal cell carcinoma assessed by contrast-enhanced computed tomography

The application of positive psychology in the practice of education

Comparison of SHF and SSF of wet exploded corn stover and loblolly pine using in-house enzymes produced from T. reesei RUT C30 and A. saccharolyticus

Metastatic breast cancer: prolongation of survival in routine care is restricted to hormone-receptor- and Her2-positive tumors

Analytical solutions for systems of partial differential–algebraic equations

Bolus ingestion of individual branched-chain amino acids alters plasma amino acid profiles in young healthy men

Closure of small and medium size umbilical hernias with the Proceed Ventral Patch in obese patients: a single center experience

Biological dosimetry for breast cancer radiotherapy: a comparison of external beam and intraoperative radiotherapy

Confidentiality and treatment decisions of minor clients: a health professional’s dilemma & policy makers challenge

STRUCTURE PLOT: a program for drawing elegant STRUCTURE bar plots in user friendly interface

Coating of magnetite with mercapto modified rice hull ash silica in a one-pot process

Sibling relationships as a resource for coping with traumatic events

Contribution of dynamic sentinel lymphoscintigraphy images to the diagnosis of patients with malignant skin neoplasms in the upper and lower extremities

Assessment of nitrate-N contamination in the Chunnakam aquifer system, Jaffna Peninsula, Sri Lanka

Health resource utilization associated with skeletal-related events in patients with advanced breast cancer: results from a prospective, multinational observational study

Age effects on tinnitus and hearing loss in CBA/CaJ mice following sound exposure

Decentralized automatic generation control of interconnected power systems incorporating asynchronous tie-lines

Epidemiological studies on Dermatophytosis in human patients in Himachal Pradesh, India

Infrared pupillometry, the Neurological Pupil index and unilateral pupillary dilation after traumatic brain injury: implications for treatment paradigms

Implementing a seventh-order linear multistep method in a predictor-corrector mode or block mode: which is more efficient for the general second order initial value problem

Percutaneous sclerotherapy for venous malformations in the extremities: clinical outcomes and predictors of patient satisfaction

Biobased carbon content of resin extracted from polyethylene composite by carbon-14 concentration measurements using accelerator mass spectrometry

Cloning and heterologous expression of cellulose free thermostable xylanase from Bacillus brevis

Association between the serum concentration of triiodothyronine with components of metabolic syndrome, cardiovascular risk, and diet in euthyroid post-menopausal women without and with metabolic syndrome

C1 posterior arch screw as an auxiliary anchor in posterior reconstruction for atlantoaxial dislocation associated with type II odontoid fracture: a case report and review of the literature

Significance of debriefing methods in simulation-based sedation training courses for medical safety improvement in Japan

Participation and significance of self-help groups for social development: exploring the community capacity in Ethiopia

Endurance-training in healthy men is associated with lesser exertional breathlessness that correlates with circulatory-muscular conditioning markers in a cross-sectional design

Reliability of environmental sampling culture results using the negative binomial intraclass correlation coefficient

Arthritis Robustus: review of a case of an “abnormal” rheumatoid

Rare aggressive natural killer cell leukemia presented with bone marrow fibrosis - a diagnostic challenge

Generalized higher (U,M)-derivations in prime Γ-Rings

Antityphoid and radical scavengingproperties of the methanol extracts and compounds from the aerial part of Paullinia pinnata

Efficient genomic DNA extraction protocol from medicinal rich Passiflora foetida containing high level of polysaccharide and polyphenol

miRNAs in Sera of Tunisian patients discriminate between inflammatory breast cancer and non-inflammatory breast cancer

Magnetic resonance imaging features of breast cancer according to intrinsic subtypes: correlations with neoadjuvant chemotherapy effects

Neem (Azadirachta indica L.) leaf extract deteriorates oocyte quality by inducing ROS-mediated apoptosis in mammals

Effect on β-galactosidase synthesis and burden on growth of osmotic stress in Escherichia coli

Changes in ovarian function in premenopausal women with breast cancer undergoing adjuvant TC (docetaxel and cyclophosphamide) chemotherapy during a brief period of amenorrhea around the last chemotherapy cycle

Altered coronary artery calcium scores before bariatric surgery

Self-parameterized active contours based on regional edge structure for medical image segmentation

Indigenous students transitioning to school: responses to pre-foundational mathematics

Novel pervasive scenarios for home management: the Butlers architecture

Submerged goiter proven to be metastatic infiltration of a neuro-endocrine Merkel cell carcinoma

Personal travel blogs as texts for studying intercultural interactions: a pilot test case study of an American sojourner’s blogs from Zimbabwe

Application of the SP theory of intelligence to the understanding of natural vision and the development of computer vision

Alternating sums of reciprocal generalized Fibonacci numbers

Exact solutions for (1 + 1)-dimensional nonlinear dispersive modified Benjamin-Bona-Mahony equation and coupled Klein-Gordon equations

Effect of idol immersion on water quality and Tilapia fish in Futala, Gandhisagar and Ambazari lakes of Nagpur, India

Laparoscopic placement of a tined lead electrode on the pudendal nerve with urodynamic monitoring of bladder function during electrical stimulation: an acute experimental study in healthy female pigs

Molecular diversity and functionalvariability of environmental isolates of Bacillusspecies

Ileocecal ulcers accompanied by relapsing polychondritis: a case report

Identification of novel microRNAs in the Verticillium wilt-resistant upland cotton variety KV-1 by high-throughput sequencing

Hypouricemic effect and safety of febuxostat used for prevention of tumor lysis syndrome

Isotretinoin-induced skeletal hyperostosis

Giant bypass aneurysm, a cause of suspected cardiac mass

Feature selection and semi-supervised clustering using multiobjective optimization

Outcome of decompressive craniectomy in comparison to nonsurgical treatment in patients with malignant MCA infarction

Land cover transformation in two post-mining landscapes subjected to different ages of reclamation since dumping of spoils

Effect of confinement pressure on bearing capacity of two samples of square and strip footing (numerical study)

Intensity-Duration-Frequency (IDF) rainfall curves, for data series and climate projection in African cities

The association in a two-way contingency table through log odds ratio analysis: the case of Sarno river pollution

Biological removal of phenol from saline wastewater using a moving bed biofilm reactor containing acclimated mixed consortia

Mixed Bartter-Gitelman syndrome: an inbred family with a heterogeneous phenotype expression of a novel variant in the CLCNKB gene

Statistical design and optimization of single cell oil production from sugarcane bagasse hydrolysate by an oleaginous yeast Rhodotorula sp. IIP-33 using response surface methodology

Regional distribution of mercury in sediments of the main rivers of French Guiana (Amazonian basin)

Predictors for mortality in hospitalized patients with chronic obstructive pulmonary disease

Feasibility and appropriateness of recommended sorghum production technologies

Left-handed sperm removal by male Calopteryx damselflies (Odonata)

Fast digital zooming system using directionally adaptive image interpolation and restoration

High phosphoserine in sepsis: panel of clinical and plasma amino acid correlations

Sex- and season-dependent differences in telomere length and telomerase activity in the leaves of ash and willow

Multiculturalism in social agencies for the aged

Analysis of flow parameters of a Newtonian fluid through a cylindrical collapsible tube

The ATRX cDNA is prone to bacterial IS10 element insertions that alter its structure

Emergence of altruism behavior in army ant-based social evolutionary system

Knowing the enemy: ant behavior and control in a pediatric hospital of Buenos Aires

Identification of a Geranylgeranyl reductase gene for chlorophyll synthesis in rice

Prognostic significance of histological invasion in high grade soft tissue sarcomas

fAFLP analysis of Brazilian Bacillus thuringiensis isolates

A modified data normalization method for GC-MS-based metabolomics to minimize batch variation

A new device for simple and accurate urinary pH testing by the Stone-former patient

Assessment of the effect of Schistosoma haematobium co infection on malaria parasites and immune responses in rural populations in Gabon: study protocol

The influence of acute hypoxic exposure on isokinetic muscle force production

An approach for aggregating upstream catchment information to support research and management of fluvial systems across large landscapes

A bio-inspired feature extraction for robust speech recognition

The second study of experimental human folate deficiency

Effect of pumpkin on the quality characteristics and storage quality of aerobically packaged chicken sausages

The treatment and survival of patients with triple negative breast cancer in a London population

Differential regulation of c-Met signaling pathways for synovial cell function

Arylamine N-acetyl Transferase (NAT) in the blue secretion of Telescopium telescopium: xenobiotic metabolizing enzyme as a biomarker for detection of environmental pollution

An aerial spot-spraying technique: a pilot study to test a method for pest eradication in urban environments

Design of static synchronous series compensator based damping controller employing invasive weed optimization algorithm

Minimal invasive management of traumatic transection of the vertebral artery

The grand old party – a party of values?

Location of α-tocopherol and α-tocotrienol to heterogeneous cell membranes and inhibition of production of peroxidized cholesterol in mouse fibroblasts

Comparison of generalist predators in winter-flooded and conventionally managed rice paddies and identification of their limiting factors

Investigating the relationship between peak inspiratory flow rate and volume of inhalation from a Diskus™ Inhaler and baseline spirometric parameters: a cross-sectional study

Dynamics of natural populations of the dertitivorous mudsnail Potamopyrgus antipodarum (Gray) (Hydrobiidae) in two interconnected Lakes differing in trophic state

Bio-ethanol production through simultaneous saccharification and co-fermentation (SSCF) of a low-moisture anhydrous ammonia (LMAA)-pretreated napiegrass (Pennisetum purpureum Schumach)

Vascularity of the urethra in continent women using colour doppler high-frequency endovaginal ultrasonography

Cloning and characterization of the N-methyl-D-aspartate receptor subunit NR1 gene from chum salmon, Oncorhynchus keta (Walbaum, 1792)

Effects of acute bouts of physical activity on children's attention: a systematic review of the literature

Effects of cervical muscle fatigue on the perception of the subjective vertical and horizontal

Painful plantar heel spur treatment with Co-60 teletherapy: factors influencing treatment outcome

Exact traveling wave solutions of modified KdV–Zakharov–Kuznetsov equation and viscous Burgers equation

Characterization of Actinomycetes and Trichoderma spp. for cellulase production utilizing crude substrates by response surface methodology

Urinary ATP and visualization of intracellular bacteria: a superior diagnostic marker for recurrent UTI in renal transplant recipients?

Numerical modeling of radionuclide migration through a borehole disposal site

In-house development of an FPGA-based MCA8K for gamma-ray spectrometer

Laparoscopic total gastrectomy using the transorally inserted anvil (OrVil™): a preliminary, single institution experience

Pelvic peritonitis during biologic therapy for rheumatoid arthritis: a case report and review of the literature

Testing predictive models of positive and negative affect with psychosocial, acculturation, and coping variables in a multiethnic undergraduate sample

Local uniqueness solution of illuminated solar cell intrinsic electrical parameters

Are Americans more successful at building intercultural relations than Japanese? A comparison and analysis of acculturation outcomes in Japan

Hypertensive encephalopathy and cerebral infarction

Carbon nanodots interference with lactate dehydrogenase assay in human monocyte THP-1 cells

Effect of ATG initiation codon context motifs on the efficiency of translation of mRNA derived from exogenous genes in the transgenic silkworm, Bombyx mori

Modulation of Cerrena unicolor laccase and manganese peroxidase production

Bioremoval of the synthetic dye malachite green by marine Trichoderma sp

Diversity in 113 cowpea [Vigna unguiculata (L) Walp] accessions assessed with 458 SNP markers

Effects of mutations and deletions in the human optineurin gene

Methylphenidate off-label use and safety

Physicians’ perception and attitude toward electronic medical record

Sensitivity and specificity of PET/CT regarding the detection of lymph node metastases in prostate cancer recurrence

Carotid blood flow, cardiovascular and endocrine responses during head-up tilt in patients with acute cerebrovascular diseases

Clinicopathologic characteristics of SALL4-immunopositive hepatocellular carcinoma

Taurine is absent from amino components in fruits of Opuntia ficus-indica

A comparative study of fluoride ingestion levels, serum thyroid hormone & TSH level derangements, dental fluorosis status among school children from endemic and non-endemic fluorosis areas

Prosthetic valve endocarditis due to Streptococcus pneumoniae

Empyema, acute respiratory failure, and septic shock after aspiration of a soft-shelled turtle (Pelodiscus sinensis) bone by an adult

Pigeonpea genotypes influence parasitization preference and survival and development of the Helicoverpa armigera larval parasitoid, Campoletis chlorideae

Sparse tensor phase space Galerkin approximation for radiative transport

Complete larval development of the Monkey River Prawn Macrobrachium lar (Palaemonidae) using a novel greenwater technique

Bibliometric analysis of nutrition and dietetics research activity in Arab countries using ISI Web of Science database

Cytotoxic effects of the compound cis-tetraammine(oxalato)ruthenium(III) dithionate on K-562 human chronic myelogenous leukemia cells

High frequency input impedance modeling of low-voltage residential installations - influence on lightning overvoltage simulations results

Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes

Identification and cost of adverse events in metastatic breast cancer in taxane and capecitabine based regimens

Evaluation of mycotoxin sequestering agents for aflatoxin and deoxynivalenol: an in vitro approach

A poor prognostic case of peripheral T-cell lymphoma in the base of tongue with chemotherapy followed by radiation therapy

Clinical and genetic characterization of basal cell carcinoma and breast cancer in a single patient

Examining the potential impacts of climate change on international security: EU-Africa partnership on climate change

Implications of a novel Pseudomonas species on low density polyethylene biodegradation: an in vitro to in silico approach

Assessment of clonal fidelity of Tylophora indica (Burm. f.) Merrill “in vitro” plantlets by ISSR molecular markers

Validation of assay indicating method development of meloxicam in bulk and some of its tablet dosage forms by RP-HPLC

A prospective study of grey matter and cognitive function alterations in chemotherapy-treated breast cancer patients

Improving osseointegration of Co-Cr by nanostructured titanium coatings

Review of interdisciplinary devices for detecting the quality of ship ballast water

Statistical optimization of fibrinolytic enzyme production by Pseudoalteromonas sp. IND11 using cow dung substrate by response surface methodology

Glass transition temperature of dried lens tissue pretreated with trehalose, maltose, or cyclic tetrasaccharide

Long term follow up of breast cancer patients treated with acupuncture for hot flashes

Properties of GPS noise at Japan islands before and after Tohoku mega-earthquake

Pentoxifylline decreases glycemia levels and TNF-alpha, iNOS and COX-2 expressions in diabetic rat pancreas

Effects of prostacyclin on the early inflammatory response in patients with traumatic brain injury-a randomised clinical study

The impact of age and sex on healthcare expenditure of households in Bangladesh

An unusual high bifurcation and variable branching of the axillary artery in a Greek male cadaver

Symptomatic cluster headache: a review of 63 cases

Selection of high temperature and salinity tolerant Trichoderma isolates with antagonistic activity against Sclerotium rolfsii

Development of cereal and legume based food products for the elderly

Metabolism under hypoxia in Tm1 murine melanoma cells is affected by the presence of galectin-3, a metabolomics approach

Application of direct PCR in rapid rDNA ITS haplotype determination of the hyperparasitic fungus Sphaeropsis visci (Botryosphaeriaceae)

Modeling of HIV/AIDS dynamic evolution using non-homogeneous semi-markov process

Expression of endogenous Mkp1 in 6-OHDA rat models of Parkinson’s disease

In search of an empowering and motivating personal wellbeing pathway for Finnish heart patients

Selective internal radiation therapy of hepatic tumors: procedural implications of a patent hepatic falciform artery

Computerized database management system for breast cancer patients

Bimini Islands: a characterization of the two major nursery areas; status and perspectives

Pre-service ultrasonic and manual evaluation of the reproductive organs of dairy cows presumed to be in estrus

Isolation and molecular identification of the etiological agents of streptococcosis in Nile tilapia (Oreochromis niloticus) cultured in net cages in Lake Sentani, Papua, Indonesia

SENTIA: a systematic online monitoring registry for children and adolescents treated with antipsychotics

Quantitative analysis of vascular signs on early postmortem multi-detector computed tomography

The best triathletes are older in longer race distances – a comparison between Olympic, Half-Ironman and Ironman distance triathlon

Nutrition habits in 24-hour mountain bike racers

Acceptability and intended usage preferences for six HIV testing options among internet-using men who have sex with men

Development of clinical pharmacy services for intensive care units in Korea

Breast 3 T-MR imaging: indication for stereotactic vacuum-assisted breast biopsy

Gastrointestinal perforation due to vasculitis at primary diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA) despite a high dose glucocorticosteroids treatment

Towards institutionalised regionalism: the role of institutions and prospects for institutionalisation in ASEAN

Field models and numerical dosimetry inside an extremely-low-frequency electromagnetic bioreactor: the theoretical link between the electromagnetically induced mechanical forces and the biological mechanisms of the cell tensegrity

Colonic atresia and anorectal malformation in a Haitian patient: a case study of rare diseases

Single-breath-hold whole-heart coronary MRA in healthy volunteers at 3.0-T MRI

Occurrence of Vibrio and Salmonella species in mussels (Mytilus galloprovincialis) collected along the Moroccan Atlantic coast

Microbiota from Litopenaeus vannamei: digestive tract microbial community of Pacific white shrimp (Litopenaeus vannamei)

Delayed abdominal wall abscess after abdomino-perineal resection simulating local recurrence of rectal cancer

Cloning, phylogeny, and expression analysis of the Broad-Complex gene in the longicorn beetle Psacothea hilaris

Dorsal penile nerve block for robot-assisted radical prostatectomy catheter related pain: a randomized, double-blind, placebo-controlled trial

Rotationally inelastic dynamics of LiH (X1Σ+, v = 0) in collisions with Ar: State-to-state inelastic rotational rate coefficients

Effect of an exercise training intervention with resistance bands on blood cell counts during chemotherapy for lung cancer: a pilot randomized controlled trial

Trigonometrically-fitted second derivative method for oscillatory problems

Greenhouse gas emissions from sub-tropical agricultural soils after addition of organic by-products

Spatial-temporal distribution of salinity and temperature in the Oued Loukkos estuary, Morocco: using vertical salinity gradient for estuary classification

Thin films with high surface roughness: thickness and dielectric function analysis using spectroscopic ellipsometry

Benchmarking network for clinical and humanistic outcomes in diabetes (BENCH-D) study: protocol, tools, and population

Comparison of treatment patterns and economic outcomes in metastatic breast cancer patients initiated on trastuzumab versus lapatinib: a retrospective analysis

A study of Aspergillus niger- hydrolyzed cassava peel meal as a carbohydrate source on the histology of broiler chickens

Investigating the insecticidal potential of Geomyces (Myxotrichaceae: Helotiales) and Mortierella (Mortierellacea: Mortierellales) isolated from Antarctica

Female sexual function after transobturator tape in women with urodynamic stress urinary incontinence

Extent of podoconiosis-related stigma in Wolaita Zone, Southern Ethiopia: a cross-sectional study

Oscillation theorems for second order nonlinear forced differential equations

Successful surgical in situ treatment of prosthetic graft infection by staged procedure after Bentall operation and total aortic arch replacement

Evaluation of the nutritive value of muiumba (Baikiaea plurijuga) seeds: chemical composition, in vitro organic matter digestibility and in vitro gas production

Effect of gibberellic acid (GA), indole acetic acid (IAA) and benzylaminopurine (BAP) on the synthesis of essential oils and the isomerization of methyl chavicol and trans-anethole in Ocimum gratissimum L

Visual function of drivers and its relationship to road traffic accidents in Urban Africa

Risk-driven security testing using risk analysis with threat modeling approach

Prospective evaluation of fluorescence-guided cystoscopy to detect bladder cancer in a high-risk population: results from the UroScreen-Study

Adult adipose-derived stem cells and breast cancer: a controversial relationship

Embryo sac formation and early embryo development in Agave tequilana (Asparagaceae)

Motivating students’ participation in a computer networks course by means of magic, drama and games

Phase II study of lapatinib in combination with vinorelbine, as first or second-line therapy in women with HER2 overexpressing metastatic breast cancer

A comprehensive review of urologic complications in patients with diabetes

Comparison of intelligence, weight and height in children after general anesthesia with and without perioperative desaturation in non-cardiac surgery: a historical and concurrent follow-up study

Realist explanatory theory building method for social epidemiology: a protocol for a mixed method multilevel study of neighbourhood context and postnatal depression

Longitudinal changes in insulin sensitivity, insulin secretion, beta cell function and glucose effectiveness during development of non-diabetic hyperglycemia in a Japanese population

The use of FOCUS Harmonic scalpel compared to conventional haemostasis (knot and tie ligation) for thyroid surgery: a prospective randomized study

Solution of underdetermined systems of equations with gridded a priori constraints

Approaches for the design of reduced toxicant emission cigarettes

Volumetry may predict early renal function after nephron sparing surgery in solitary kidney patients

Evaluation of antioxidant activities of extracts from 19 Chinese edible flowers

Public assessment of key performance indicators of healthcare in a Canadian province: the effect of age and chronic health problems

Indirect shoot organogenesis from leaf explants of Adhatoda vasica Nees

Erratum to: the ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma

MUC1 gene polymorphism rs4072037 and susceptibility to gastric cancer: a meta-analysis

Relationship between bases of power and job stresses: role of mentoring

Prospective, comprehensive, and effective viral monitoring in Cuban children undergoing solid organ transplantation

Factors influencing anti-asthmatic generic drug consumption in Morocco: 1999-2010

ASTER, ALI and Hyperion sensors data for lithological mapping and ore minerals exploration

Chemotherapy dose reduction due to chemotherapy induced peripheral neuropathy in breast cancer patients receiving chemotherapy in the neoadjuvant or adjuvant settings: a single-center experience

Ganoderma formosanum polysaccharides attenuate Th2 inflammation and airway hyperresponsiveness in a murine model of allergic asthma

Survival analyses of postoperative lung cancer patients: an investigation using Japanese administrative data

Construction of the membership surface of imprecise vector

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Year: 2014, Volume: 3, Issue: Suppl 1

Year: 2014, Volume: 3, Issue: 1

Year: 2013, Volume: 2

Year: 2012, Volume: 1

Interim analysis for binary outcome trials with a long fixed follow-up time and repeated outcome assessments at pre-specified times

Content Provider	PubMed Central
Author	Sameer, Parpia Julian, Jim A. Gu, Chushu Thabane, Lehana Levine, Mark N.
Abstract	In trials with binary outcomes, assessed repeatedly at pre-specified times and where the subject is considered to have experienced a failure at the first occurrence of the outcome, interim analyses are performed, generally, after half or more of the subjects have completed follow-up. Depending on the duration of accrual relative to the length of follow-up, this may be inefficient, since there is a possibility that the trial will have completed accrual prior to the interim analysis. An alternative is to plan the interim analysis after subjects have completed follow-up to a time that is less than the fixed full follow-up duration. Using simulations, we evaluated three methods to estimate the event proportion for the interim analysis in terms of type I and II errors and the probability of early stopping. We considered: 1) estimation of the event proportion based on subjects who have been followed for a pre-specified time (less than the full follow-up duration) or who experienced the outcome; 2) estimation of the event proportion based on data from all subjects that have been randomized by the time of the interim analysis; and 3) the Kaplan-Meier approach to estimate the event proportion at the time of the interim analysis. Our results show that all methods preserve and have comparable type I and II errors in certain scenarios. In these cases, we recommend using the Kaplan-Meier method because it incorporates all the available data and has greater probability of early stopping when the treatment effect exists.
Related Links	http://dx.doi.org/10.1186/2193-1801-3-323
Starting Page	323
File Format	PDF
ISSN	21931801
e-ISSN	21931801
Journal	SpringerPlus
Volume Number	3
Language	English
Publisher	Springer International Publishing
Publisher Date	2014-01-01
Access Restriction	Open
Rights Holder	Springer International Publishing
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in