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  1. Ultrasound in medicine & biology
  2. Year: 2014, Volume: 40
  3. Year: 2014, Volume: 40, Issue: 3
  4. In Vitro Acoustic Characterization of Three Phospholipid Ultrasound Contrast Agents from 12 to 43 MHz
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Year: 2016, Volume: 42
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Year: 2014, Volume: 40
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Year: 2014, Volume: 40, Issue: 4
Year: 2014, Volume: 40, Issue: 3
In Vitro Acoustic Characterization of Three Phospholipid Ultrasound Contrast Agents from 12 to 43 MHz
Year: 2014, Volume: 40, Issue: 2
Year: 2014, Volume: 40, Issue: 1
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In Vitro Acoustic Characterization of Three Phospholipid Ultrasound Contrast Agents from 12 to 43 MHz

Content Provider PubMed Central
Author Sun, Chao Sboros, Vassilis Butler, Mairead B. Moran, Carmel M.
Copyright Year 2014
Abstract The acoustic properties of two clinical (Definity, Lantheus Medical Imaging, North Billerica, MA, USA; SonoVue, Bracco S.P.A., Milan, Italy) and one pre-clinical (MicroMarker, untargeted, Bracco, Geneva, Switzerland; VisualSonics, Toronto, ON, Canada) ultrasound contrast agent were characterized using a broadband substitution technique over the ultrasound frequency range 12–43 MHz at 20 ± 1°C. At the same number concentration, the acoustic attenuation and contrast-to-tissue ratio of the three native ultrasound contrast agents are comparable at frequencies below 30 MHz, though their size distributions and encapsulated gases and shells differ. At frequencies above 30 MHz, native MicroMarker has higher attenuation values and contrast-to-tissue ratios than native Definity and SonoVue. Decantation was found to be an effective method to alter the size distribution and concentration of native clinical microbubble populations, enabling further contrast enhancement for specific pre-clinical applications.
Related Links http://dx.doi.org/10.1016/j.ultrasmedbio.2013.10.010
Ending Page 550
Page Count 10
Starting Page 541
File Format PDF
ISSN 03015629
e-ISSN 1879291X
Journal Ultrasound in Medicine & Biology
Issue Number 3
Volume Number 40
Language English
Publisher Pergamon Press
Publisher Date 2014-03-01
Access Restriction Open
Rights Holder Pergamon Press
Subject Keyword Biophysics Radiological and Ultrasound Technology Radiology Nuclear Medicine and imaging Research in Higher Education
Content Type Text
Resource Type Article
Subject Radiology, Nuclear Medicine and Imaging Acoustics and Ultrasonics Biophysics Radiological and Ultrasound Technology
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